Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Department of Ophthalmology, University Hospital Zurich, Zurich, Switzerland.
J Eur Acad Dermatol Venereol. 2022 Jan;36 Suppl 1:59-62. doi: 10.1111/jdv.17529.
Cutaneous squamous cell carcinoma (cSCC) is the most common tumour entity that grows secondarily into the orbital area, while basal cell carcinoma (BCC) is the most common periocular and eyelid tumour. Diagnostic delays are common and may increase post-treatment complications. The therapy is challenging and must be discussed at an interdisciplinary tumour board. We discuss four cases of cSCC with orbital invasion treated with immune-checkpoint inhibitors with variable responses.
皮肤鳞状细胞癌 (cSCC) 是最常见的继发到眼眶区域的肿瘤实体，而基底细胞癌 (BCC) 是最常见的眼周和眼睑肿瘤。诊断延迟很常见，可能会增加治疗后的并发症。治疗具有挑战性，必须在多学科肿瘤委员会上进行讨论。我们讨论了四例接受免疫检查点抑制剂治疗的伴眼眶侵犯的 cSCC 病例，这些患者的反应各不相同。
