Kmietzyk H J, Piatkowski J, Planitzer J
Fortschr Neurol Psychiatr. 1986 Feb;54(2):42-6. doi: 10.1055/s-2007-1001848.
The Controlateral Pain Flexor Reflex (CPFR) is demonstrated by a case study of a thalamic syndrome with a typical thalamic hand, thalamic foot, and thalamic pain crisis. Mechanical triggering by a painful irritation on the healthy hand side leads to a stronger motoric-nocifensic reflex response of the contralateral extremities. On the other hand the healthy person would develop an ipsilateral nocifensic response only. In the case reported here, the electrically evoked CPFR led to the same result, and simultaneously caused disappearance of the thalamic pain, since this kind of management represents therapeutical approach via the endorphin system. In respect of the pathophysiological basis of the thalamic modified nocifensic reflex response, we are inclined to believe that painful stimulation evokes an accentuated flexor reaction if the thalamic-controlled influences are omitted by a lesion of the specific nuclei.
通过对一例伴有典型丘脑手、丘脑足和丘脑疼痛危象的丘脑综合征的病例研究，证实了对侧疼痛屈肌反射（CPFR）。健康侧手部的疼痛刺激引发的机械性触发会导致对侧肢体出现更强的运动-伤害性反射反应。另一方面，健康人只会产生同侧伤害性反应。在本报告的病例中，电诱发的CPFR导致了相同的结果，同时引起了丘脑疼痛的消失，因为这种处理方式代表了通过内啡肽系统的治疗方法。关于丘脑改变的伤害性反射反应的病理生理基础，我们倾向于认为，如果特定核团的损伤消除了丘脑控制的影响，疼痛刺激会引发增强的屈肌反应。
