Sakakibara T, Hirose H, Nakano S, Matsuda H, Kawachi K, Kitamura S, Kawashima Y
Nihon Geka Gakkai Zasshi. 1986 Jan;87(1):90-8.
Left ventricular function and coronary sinus blood flow at rest and during exercise were evaluated in 27 patients after aortocoronary bypass surgery and in 13 normal subjects (G-C). Twenty patients (G-1) had successfully revascularized left anterior descending artery (LAD). In 7 patients (G-2), the revascularization for LAD was not complete. There was no difference among 3 groups in stroke work index (SWI), left ventricular end-diastolic pressure (LVEDP) and coronary sinus blood flow (CSF) at rest. SWI during exercise in G-2 (44.7 +/- 14.7 g. M/beat/m2) was significantly lower than that in G-1 and G-C (67.9 +/- 15.0, 77.2 +/- 17.0 g.M/beat/m2) (p less than 0.02, p less than 0.002). LVEDP during exercise in G-2 (32 +/- 6 mmHg) was significantly higher than that in G-1, G-C (17 +/- 7, 13 +/- 3 mmHg) (p less than 0.001, p less than 0.001). CSF during exercise in G-2 (160 +/- 64 ml/min) was significantly lower than that in G-1, G-C (357 +/- 79, 290 +/- 113 ml/min) (p less than 0.001, p less than 0.002). These data indicated that left ventricular function during exercise and coronary sinus blood flow reserve for exercise in patient with completely revascularized LAD was significantly better than that in patients with incompletely revascularized LAD.
对27例接受主动脉冠状动脉搭桥手术后的患者和13名正常受试者（G - C组）在静息和运动状态下的左心室功能及冠状窦血流量进行了评估。20例患者（G - 1组）左前降支（LAD）成功实现血管重建。7例患者（G - 2组）LAD的血管重建未完成。三组在静息时的每搏功指数（SWI）、左心室舒张末期压力（LVEDP）和冠状窦血流量（CSF）方面无差异。G - 2组运动时的SWI（44.7±14.7 g·M/次/平方米）显著低于G - 1组和G - C组（67.9±15.0、77.2±17.0 g·M/次/平方米）（p＜0.02，p＜0.002）。G - 2组运动时的LVEDP（32±6 mmHg）显著高于G - 1组、G - C组（17±7、13±3 mmHg）（p＜0.001，p＜0.001）。G - 2组运动时的CSF（160±64 ml/分钟）显著低于G - 1组、G - C组（357±79、290±113 ml/分钟）（p＜0.001，p＜0.002）。这些数据表明，LAD完全血管重建患者运动时的左心室功能及运动时冠状窦血流量储备显著优于LAD血管重建不完全的患者。
