From the Department of Surgical Sciences, Section of Anaesthesiology and Intensive Care Medicine, Uppsala University, Uppsala, Sweden (PF, HA, AK), the Unit for Research & Innovation, Department of Paediatric Anaesthesia, Istituto Giannina Gaslini, Genova, Italy (ND), the Clinic of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany (CB, RS), the Department of Anaesthesiology and Intensive Care, Hospices Civils de Lyon, Femme Mère Enfant Hospital, Lyon, France (LB, EC, MDQS), the Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA (EE, RI, PAS), the Department of Anesthesia, University Children's Hospital, Zurich, Switzerland (JH, FK, ASc), the Children's Hospital of Eastern Ontario, University of Ottawa (DRo), the University of Ottawa, Ottawa, Ontario, Canada (DRo), the Department of Anesthesia, Pediatric Intensive Care and Emergency Medicine, Auf der Bult Children's Hospital, Hannover, Germany (DRu), Stanford University - School of Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Palo Alto, California, USA (ARS), the Sackler Faculty of Medicine, Tel Aviv University, Israel - Division of Anesthesia, Pain and Intensive Care, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel (DS), Great Ormond St. Hospital, London, United Kingdom (MT), the Clinique d'Anesthésie Pédiatrique, Hôpital Jeanne de Flandre, CHRU de Lille, France (FV), the Department of Paediatric and Obstetric Anaesthesia, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark (AA).
Eur J Anaesthesiol. 2022 Jan 1;39(1):4-25. doi: 10.1097/EJA.0000000000001599.
Current paediatric anaesthetic fasting guidelines have recommended conservative fasting regimes for many years and have not altered much in the last decades. Recent publications have employed more liberal fasting regimes with no evidence of increased aspiration or regurgitation rates. In this first solely paediatric European Society of Anaesthesiology and Intensive Care (ESAIC) pre-operative fasting guideline, we aim to present aggregated and evidence-based summary recommendations to assist clinicians, healthcare providers, patients and parents. We identified six main topics for the literature search: studies comparing liberal with conservative regimens; impact of food composition; impact of comorbidity; the use of gastric ultrasound as a clinical tool; validation of gastric ultrasound for gastric content and gastric emptying studies; and early postoperative feeding. The literature search was performed by a professional librarian in collaboration with the ESAIC task force. Recommendations for reducing clear fluid fasting to 1 h, reducing breast milk fasting to 3 h, and allowing early postoperative feeding were the main results, with GRADE 1C or 1B evidence. The available evidence suggests that gastric ultrasound may be useful for clinical decision-making, and that allowing a 'light breakfast' may be well tolerated if the intake is well controlled. More research is needed in these areas as well as evaluation of how specific patient or treatment-related factors influence gastric emptying.
当前的儿科麻醉禁食指南多年来一直推荐保守的禁食方案,在过去几十年中变化不大。最近的出版物采用了更为宽松的禁食方案,但没有证据表明反流和误吸率增加。在这首个完全由欧洲麻醉学会和重症监护学会(ESAIC)制定的儿科术前禁食指南中,我们旨在提供综合和基于证据的总结建议,以协助临床医生、医疗保健提供者、患者和家长。我们确定了六个主要的文献搜索主题:比较宽松与保守方案的研究;食物成分的影响;合并症的影响;胃超声作为临床工具的使用;胃超声对胃内容物和胃排空研究的验证;以及术后早期喂养。文献检索由专业图书馆员与 ESAIC 工作组合作完成。主要结果是减少清液禁食至 1 小时,减少母乳禁食至 3 小时,并允许术后早期喂养,证据等级为 1C 或 1B。现有证据表明,胃超声可能有助于临床决策,如果摄入得到很好的控制,允许“清淡早餐”可能是可以耐受的。还需要在这些领域进行更多的研究,以及评估特定患者或治疗相关因素如何影响胃排空。