Hashimoto Yoshitaka, Yasuzawa Hisami, Ishida Tsutomu, Miyazaki Yuichi, Fukui Michiaki
Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.
Medical Affairs Department, Sanwa Kagaku Kenkyusho Co., Ltd., 35 Higashisotobori-cho, Higashi-ku, Nagoya, Aichi 461-8631, Japan.
J Clin Biochem Nutr. 2021 Nov;69(3):286-293. doi: 10.3164/jcbn.21-5. Epub 2021 May 7.
To investigate the patients' consciousness regarding the use of metformin and medical cost in Japanese patients with type 2 diabetes taking metformin. This cross-sectional study investigated patients' general characteristics and consciousness regarding medical cost, kidney function, liver function, and metformin usage, using a self-administered, internet-based questionnaire. Among 1,000 patients, 81.0% felt unsatisfied with treatment for type 2 diabetes, with the main reason for dissatisfaction being high medical cost, with 540 patients reporting this. In addition, 16.8% of patients experienced treatment disruption and among them, 48.2% (81/168) answered that the reason was high medical cost. Over half of the patients did not understand their kidney and liver functions, respectively. Only 8.9% and 7.1% of patients knew both the words and meanings behind sick days and lactic acidosis, respectively. In conclusion, many patients with type 2 diabetes taking metformin were not satisfied with their treatments, with the main reason being high medical cost. Moreover, they did not have sufficient knowledge of sick days and/or lactic acidosis.
调查日本服用二甲双胍的2型糖尿病患者对二甲双胍使用情况及医疗费用的认知。这项横断面研究使用基于互联网的自填式问卷调查了患者的一般特征以及对医疗费用、肾功能、肝功能和二甲双胍使用情况的认知。在1000名患者中，81.0%对2型糖尿病治疗不满意，主要不满意原因是医疗费用高，有540名患者报告了这一点。此外，16.8%的患者经历过治疗中断，其中48.2%（81/168）回答原因是医疗费用高。分别有超过一半的患者不了解自己的肾功能和肝功能。只有8.9%和7.1%的患者分别知道病假和乳酸酸中毒背后的词汇及含义。总之，许多服用二甲双胍的2型糖尿病患者对治疗不满意，主要原因是医疗费用高。此外，他们对病假和/或乳酸酸中毒没有足够的了解。
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