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成功实施儿童脓毒症治疗方案的障碍及建议解决方案

Barriers and Proposed Solutions to a Successful Implementation of Pediatric Sepsis Protocols.

作者信息

Medeiros Daniela Nasu Monteiro, Shibata Audrey Ogawa, Pizarro Cristiane Freitas, Rosa Maria de Lourdes Alves, Cardoso Marta Pessoa, Troster Eduardo Juan

机构信息

Pediatric Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo, Brazil.

Health Practices Department, Hospital Municipal Dr Moysés Deutsch - M'Boi Mirim, São Paulo, Brazil.

出版信息

Front Pediatr. 2021 Nov 10;9:755484. doi: 10.3389/fped.2021.755484. eCollection 2021.

Abstract

The implementation of managed protocols contributes to a systematized approach to the patient and continuous evaluation of results, focusing on improving clinical practice, early diagnosis, treatment, and outcomes. Advantages to the adoption of a pediatric sepsis recognition and treatment protocol include: a reduction in time to start fluid and antibiotic administration, decreased kidney dysfunction and organ dysfunction, reduction in length of stay, and even a decrease on mortality. Barriers are: absence of a written protocol, parental knowledge, early diagnosis by healthcare professionals, venous access, availability of antimicrobials and vasoactive drugs, conditions of work, engagement of healthcare professionals. There are challenges in low-middle-income countries (LMIC). The causes of sepsis and resources differ from high-income countries. Viral agent such as dengue, malaria are common in LMIC and initial approach differ from bacterial infections. Some authors found increased or no impact in mortality or increased length of stay associated with the implementation of the SCC sepsis bundle which reinforces the importance of adapting it to most frequent diseases, disposable resources, and characteristics of healthcare professionals. Conclusions: (1) be simple; (2) be precise; (3) education; (5) improve communication; (5) work as a team; (6) share and celebrate results.

摘要

实施管理协议有助于采用系统化方法来对待患者并持续评估结果,重点在于改善临床实践、早期诊断、治疗及治疗效果。采用儿科脓毒症识别与治疗协议的优势包括:缩短开始补液和使用抗生素的时间、减少肾功能障碍和器官功能障碍、缩短住院时间,甚至降低死亡率。障碍包括:缺乏书面协议、家长的认知、医护人员的早期诊断、静脉通路、抗菌药物和血管活性药物的可获得性、工作条件、医护人员的参与度。低收入和中等收入国家(LMIC)存在挑战。脓毒症的病因和资源与高收入国家不同。登革热、疟疾等病毒病原体在低收入和中等收入国家很常见,其初始治疗方法与细菌感染不同。一些作者发现,实施脓毒症拯救运动(SCC)脓毒症集束化治疗对死亡率或住院时间延长有增加或无影响,这强化了使其适应最常见疾病、可用资源及医护人员特点的重要性。结论:(1)要简单;(2)要精确;(3)开展教育;(4)改善沟通;(5)团队协作;(6)分享并庆祝成果。 (注:原文中编号(4)缺失,译文按照顺序补充完整)

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