Petrillo Stefania M, Del Mauro Marianna, Lambro Benedetta E, Occhigrossi Chiara, Piccirilli Massimo
Speech and Language Therapy Degree, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
Neurol Sci. 2022 May;43(5):3065-3070. doi: 10.1007/s10072-021-05651-y. Epub 2021 Dec 2.
Primary progressive aphasia (PPA) is a neurodegenerative disease characterised by a progressive decline in language and speech as the first clinical manifestation, which mostly spares other cognitive functions. However, the linguistic impairment of PPA shows different features than that resulting from cerebrovascular diseases. The major difference between the linguistic manifestations of PPA and the traditional classification of aphasias has led to the development of new, more specific methods of language assessment. Among the currently available tools, there has been great interest in the Progressive Aphasia Severity Scale (PASS). This quick and easy-to-use clinical tool allows to collect significant information from caregivers about the communicative, linguistic, and functional difficulties of patients affected by PPA. In addition to monitoring the severity and progression of deficits in 13 different language domains, this scale integrates the classic "clinically reported" assessment with a "caregiver-reported" analysis of the daily experience of the patient, which provides a better understanding of how the disease affects the quality of life of both the patient and the caregiver. In the present contribution, the PASS was translated and adapted into Italian according to the international guidelines for the cross-cultural adaptation of self-report measures. This version of the PASS can help clinicians and researchers in the diagnosis of PPA in Italian clinical populations. Furthermore, it could be particularly useful for the long-term evaluation of the disease, in order to monitor its evolution, and might represent an optimal means to verify the efficacy of speech/language therapy in delaying the progression of the disease.
原发性进行性失语（PPA）是一种神经退行性疾病，其特征是语言和言语功能进行性下降为首发临床表现，而其他认知功能大多不受影响。然而，PPA的语言障碍表现出与脑血管疾病所致语言障碍不同的特征。PPA语言表现与传统失语症分类之间的主要差异促使了更具针对性的新语言评估方法的发展。在目前可用的工具中，渐进性失语严重程度量表（PASS）引起了极大关注。这个快速且易于使用的临床工具能够从照顾者那里收集关于PPA患者沟通、语言和功能障碍的重要信息。除了监测13个不同语言领域的缺陷严重程度和进展情况外，该量表还将经典的“临床报告”评估与对患者日常经历的“照顾者报告”分析相结合，从而更好地了解该疾病如何影响患者和照顾者的生活质量。在本论文中，根据自我报告测量跨文化适应的国际指南，将PASS翻译成意大利语并进行了改编。这个意大利语版本的PASS有助于临床医生和研究人员对意大利临床人群中的PPA进行诊断。此外，它对于疾病的长期评估可能特别有用，以便监测其进展情况，并且可能是验证言语/语言治疗在延缓疾病进展方面疗效的最佳手段。
