State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2021 Dec 1;39(6):718-723. doi: 10.7518/hxkq.2021.06.015.
To investigate the clinical effect of Er:YAG laser combined with ethylenediamine tetra acetic acid (EDTA) on three-walled periodontal intrabony defects adjacent to implant sites.
A total of 30 patients with three-walled periodontal intrabony defects adjacent to implant sites were treated with the combination therapy. Patients with three-walled intrabony defects were divided into two groups according to the depth of the intrabony pocket between the implant and natural teeth. Evaluation of wound healing was performed 10 days after the operation, and bone augmentation was evaluated 6 months after the operation.
Primary healing in group 1 was 92.31%, primary healing in group 2 was 82.35%. No significant difference was observed between the two groups (>0.05). Bone augmentation in group 1 and group 2 were (2.85±1.81), (4.92±2.22) mm. There was significant difference between the two groups (<0.05). New bone growth occurred more slowly in group 1 (0.70 mm±0.32 mm) than in group 2 (1.25 mm±0.47 mm) (>0.05). Probe depths (PD), clinical attachment levels (CAL), and sulcus bleeding indices (SBI) showed no statistically significant difference between the two groups (>0.05). The one-year survival rate of natural tooth in group 1 and group 2 were 100%, 94.2%, and the one-year survival rate of implants in both groups was 100%.
The effect of bone augmentation with combination therapy was more ideal in group 2 than in group 1. Implant placement with combination therapy may be a viable technique to reconstruct three-walled intrabony defects due to the space maintenance provided by implants and bone grafts and the good root surface biocompatibility provided by the Er:YAG laser and EDTA.
探讨 Er:YAG 激光联合乙二胺四乙酸（EDTA）治疗种植体周围三壁骨缺损的临床效果。
选择 30 例种植体周围三壁骨缺损患者，采用联合治疗。根据种植体与天然牙之间的骨内袋深度将患者分为两组。术后 10 天进行伤口愈合评价，术后 6 个月进行骨增量评价。
第 1 组的初次愈合率为 92.31%，第 2 组的初次愈合率为 82.35%。两组间差异无统计学意义（>0.05）。第 1 组和第 2 组的骨增量分别为（2.85±1.81）mm 和（4.92±2.22）mm，两组间差异有统计学意义（<0.05）。第 1 组的新骨生长速度较慢（0.70mm±0.32mm），而第 2 组较快（1.25mm±0.47mm）（>0.05）。两组间探诊深度（PD）、临床附着水平（CAL）和龈沟出血指数（SBI）差异无统计学意义（>0.05）。第 1 组和第 2 组天然牙的 1 年存活率均为 100%，种植体的 1 年存活率均为 100%。
第 2 组的骨增量效果比第 1 组更理想。联合治疗可在种植体周围三壁骨缺损中重建种植体空间，维持骨量，同时具有良好的根面生物相容性，为临床提供了一种可行的治疗方法。
