Sachdeva Surinder, Agarwal Vipin
Department of Periodontics, Himachal Institute of Dental Sciences, Paonta Sahib, Sirmour, Himachal Pradesh, India.
J Indian Soc Periodontol. 2011 Apr;15(2):130-4. doi: 10.4103/0972-124X.84381.
Chronic periodontitis is an inflammatory disorder caused by dental plaque having mixed microbial flora. The different treatment modalities available to treat this disease are aimed at removal of micro-organisms from both hard and soft tissues. Systemic as well as local anti-microbial agents are helpful adjuncts in reducing microbes especially in inaccessible areas along with mechanical debridement therapy.
The study was conducted in a split mouth design. Thirty-five patients having at least two non-adjacent sites in different quadrants with periodontal pockets ≥5 mm and with bleeding on probing at initial visit were selected. The selected sites were treated with both scaling and root planing plus tetracycline fibers or with scaling and root planing alone. Baseline and follow-up measurements included plaque index, gingival index, probing pocket depth, and clinical attachment level.
Both treatment modalities were affective in improving clinical parameters over three months' observation period. The combined antimicrobial and mechanical debridement therapy has shown better results as compared with scaling and root planing alone.
Application of tetracycline in modified collagen matrix following scaling and root planing might be beneficial in treatment of chronic periodontitis and improving periodontal parameters for 3-month duration.
慢性牙周炎是一种由含有混合微生物群落的牙菌斑引起的炎症性疾病。治疗该疾病的不同治疗方式旨在从硬组织和软组织中清除微生物。全身及局部抗菌药物是有益的辅助手段，尤其在机械清创治疗的同时，有助于减少难以触及部位的微生物。
本研究采用分口设计。选取35例患者，其不同象限至少有两个不相邻部位，牙周袋深度≥5mm，初诊时探诊出血。所选部位分别采用龈下刮治术及根面平整术加四环素纤维治疗或仅采用龈下刮治术及根面平整术治疗。基线和随访测量包括菌斑指数、牙龈指数、探诊袋深度和临床附着水平。
在三个月的观察期内，两种治疗方式均能有效改善临床参数。与单纯龈下刮治术及根面平整术相比，抗菌与机械清创联合治疗效果更佳。
在龈下刮治术及根面平整术后应用四环素于改良胶原基质中，可能有益于慢性牙周炎的治疗，并在三个月内改善牙周参数。
