Alhabashneh Rola, Darawi Obaida, Khader Yousef S, Ashour Lama
Quintessence Int. 2018;49(2):113-122. doi: 10.3290/j.qi.a39267.
To compare the 6-month clinical efficacy of Er:YAG laser and standard scalpel technique in treating gingival hyperpigmentation.
Patients requesting treatment for moderate to severe gingival hyperpigmentation in the maxilla were enrolled in this split-mouth study. The contralateral maxillary sides were randomly assigned to receive either Er:YAG laser (continuous wavelength of 2,940 nm) with a noncontact tip or the standard scalpel technique. Dummett oral pigmentation index (DOPI) and Hedin melanin index (HMI) were compared at the baseline and at 1 and 2 weeks, and 1, 3, and 6 months following the treatment. Bleeding Index, total treatment time, patient preference, pain perception at the first 3 days, wound healing, and level of satisfaction were also compared. Mann-Whitney test, Kruskal-Wallis test, and chi-square test were used to test the significance between variables. A P value of less than or equal to .05 was considered statistically significant.
Of the 22 patients enrolled, 20 completed this study. After assessing DOPI and HMI at 1 and 2 weeks, and at 1-, 3-, and 6-month follow-up appointments, both Er:YAG laser and scalpel were significantly effective in treating gingival hyperpigmentation when compared to baseline (P < .001) but with no statistically significant difference between the two treatment methods (P > .05). More patients preferred the scalpel technique as it was associated with slightly shorter treatment time and less postoperative pain when compared to Er:YAG laser, but with no statistical significance (P > .05). Er:YAG laser sites showed minimal bleeding and more rapid wound healing (P < .001).
Both Er:YAG laser and scalpel technique achieved similar outcomes regarding the efficacy of gingival depigmentation, postoperative pain perception, and the time required for the treatment. Laser therapy requires more advanced technology and is associated with higher financial costs. Therefore, the scalpel technique is still considered the gold standard treatment for gingival depigmentation.
比较铒激光(Er:YAG激光)与标准手术刀技术治疗牙龈色素沉着的6个月临床疗效。
本裂侧口研究纳入了上颌中度至重度牙龈色素沉着且要求治疗的患者。将对侧上颌随机分配接受非接触式尖端的Er:YAG激光(连续波长2940nm)或标准手术刀技术治疗。在基线、治疗后1周和2周、1个月、3个月及6个月时比较达米特口腔色素沉着指数(DOPI)和赫丁黑色素指数(HMI)。还比较了出血指数、总治疗时间、患者偏好、前3天的疼痛感知、伤口愈合情况及满意度。采用曼-惠特尼检验、克鲁斯卡尔-沃利斯检验和卡方检验来检验变量间的显著性。P值小于或等于0.05被认为具有统计学显著性。
纳入的22例患者中,20例完成了本研究。在1周和2周以及1个月、3个月和6个月随访时评估DOPI和HMI后,与基线相比,Er:YAG激光和手术刀在治疗牙龈色素沉着方面均显著有效(P < 0.001),但两种治疗方法之间无统计学显著差异(P > 0.05)。更多患者更喜欢手术刀技术,因为与Er:YAG激光相比,其治疗时间略短且术后疼痛较轻,但无统计学显著性(P > 0.05)。Er:YAG激光治疗部位出血极少且伤口愈合更快(P < 0.001)。
Er:YAG激光和手术刀技术在牙龈色素脱失疗效、术后疼痛感知及治疗所需时间方面取得了相似的结果。激光治疗需要更先进的技术且费用更高。因此,手术刀技术仍被认为是牙龈色素脱失的金标准治疗方法。