一种新型近红外诊疗探针，通过双重激活策略实现精确的癌症化疗。
A novel near-infrared theranostic probe for accurate cancer chemotherapy by a dual activation strategy.
机构信息
Key Laboratory for Green Organic Synthesis and Application of Hunan Province, Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, 411105, P. R. China.
Henan Key Laboratory of Organic Functional Molecule and Drug Innovation, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, 453007, P. R. China.
出版信息
Chem Commun (Camb). 2021 Dec 16;57(100):13768-13771. doi: 10.1039/d1cc05864a.
A novel theranostic probe called CX-B-DF is constructed for precise chemotherapy guided by near-infrared (NIR) fluorescence imaging. Moreover, the theranostic probe shows high cytotoxicity to cancer cells under dual activation (HO and TP), which causes the accuracy of drug release to be improved and the toxic side effects to be reduced.
构建了一种新型的治疗诊断探针 CX-B-DF，用于通过近红外（NIR）荧光成像进行精确的化疗引导。此外，该治疗诊断探针在双重激活（HO 和 TP）下对癌细胞表现出高细胞毒性，这导致药物释放的准确性得到提高，毒性副作用降低。
Zotero 插件