Bouvier J F, Chassard J L, Brunat-Mentigny M, Bobin J Y, Domenach M, Roojee N, Riffat G, Mayer M, Lahneche B E
Cancer. 1986 Jun 15;57(12):2280-4. doi: 10.1002/1097-0142(19860615)57:12<2280::aid-cncr2820571208>3.0.co;2-m.
Chondrosarcoma is a rare complication in hereditary multiple exostoses. The six patients in this study have had a complete follow-up and constitute the largest group of such cases to have been studied so far. Five patients had histologic evidence of malignancy. Since histologic examination can be very difficult, any other diagnostic features, may it be clinical, radiologic, or scintigraphical, should be taken into account for early surgical treatment. Bone scintigraphic examination is a valuable adjunct to early diagnosis of malignant change by showing highest uptake in malignant areas. It is also very useful for posttherapeutic follow-up.
软骨肉瘤是遗传性多发性骨软骨瘤的一种罕见并发症。本研究中的6例患者均得到了完整随访，构成了迄今为止此类病例研究中最大的一组。5例患者有恶性肿瘤的组织学证据。由于组织学检查可能非常困难，因此在早期手术治疗时应考虑任何其他诊断特征，无论是临床、放射学还是闪烁扫描学特征。骨闪烁扫描检查通过显示恶性区域的最高摄取，对恶性变的早期诊断是一种有价值的辅助手段。它对治疗后的随访也非常有用。
