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遗传性多发性骨软骨瘤的骨闪烁显像

Bone scintigraphy in hereditary multiple exostoses.

作者信息

Epstein D A, Levin E J

出版信息

AJR Am J Roentgenol. 1978 Feb;130(2):331-3. doi: 10.2214/ajr.130.2.331.

DOI:10.2214/ajr.130.2.331
PMID:414588
Abstract

Two adult patients with multiple hereditary exostoses, a skeletal disorder with recognized malignant potential, each demonstrated increased 99mTc diphosphonate uptake in an exostosis in which renewed growth had begun. None of the other multiple exostoses in either patient showed abnormal uptake. Histologic study of the lesions demonstrated chondrosarcoma in one case and benign osteochondroma in the second. Although bone scintigraphy nonspecifically identifies bone growth rather than malignant degeneration, it is more useful than radiographic bone survey in the periodic surveillance of adult patients with this disorder.

摘要

两名患有多发性遗传性骨软骨瘤的成年患者,这是一种具有公认恶性潜能的骨骼疾病,在开始重新生长的骨软骨瘤中,均显示出99mTc二膦酸盐摄取增加。两名患者的其他多发性骨软骨瘤均未显示异常摄取。对病变的组织学研究显示,一例为软骨肉瘤,另一例为良性骨软骨瘤。尽管骨闪烁显像不能特异性地识别骨生长而非恶性退变,但在对患有这种疾病的成年患者进行定期监测时,它比X线骨检查更有用。

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引用本文的文献

1
Is bone scintigraphy necessary in the initial surgical staging of chondrosarcoma of bone?骨显像在骨软骨肉瘤初始外科分期中是否必要?
Skeletal Radiol. 2012 Apr;41(4):429-36. doi: 10.1007/s00256-011-1252-x. Epub 2011 Sep 3.
2
Guidelines for paediatric bone scanning with 99mTc-labelled radiopharmaceuticals and 18F-fluoride.儿童 99mTc 标记放射性药物和 18F 氟化物骨扫描指南。
Eur J Nucl Med Mol Imaging. 2010 Aug;37(8):1621-8. doi: 10.1007/s00259-010-1492-3.
3
Bone scanning in the child and young adult. Part II.
Skeletal Radiol. 1980 Apr;5(2):65-76. doi: 10.1007/BF00347326.
4
Case report 168: chondrosarcomatous transformation in a cartilage-capped exostosis.病例报告168:骨软骨瘤的软骨肉瘤转变
Skeletal Radiol. 1981;7(2):135-8. doi: 10.1007/BF00347380.
5
Bone scanning in the child and young adult. Part I.
Skeletal Radiol. 1980 Feb;5(1):1-14. doi: 10.1007/BF00347091.
6
Unusual metastatic chondrosarcoma detected with bone scintigraphy.骨闪烁显像检测到的罕见转移性软骨肉瘤。
Eur J Nucl Med. 1986;12(5-6):306-8. doi: 10.1007/BF00251996.
7
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8
Benign osteochondromas and exostotic chondrosarcomas: evaluation of cartilage cap thickness by ultrasound.良性骨软骨瘤和外生性软骨肉瘤:超声评估软骨帽厚度
Skeletal Radiol. 1992;21(1):33-7. doi: 10.1007/BF00243091.