Department of Pathology, IPGME&R, Kolkata, India.
Department of Neurosurgery, BIN, Kolkata, India.
Cytopathology. 2022 Mar;33(2):261-265. doi: 10.1111/cyt.13084. Epub 2021 Dec 17.
Clear cell meningioma (CCM) is a rare histological variant of meningioma. It is commonly located at the cerebellopontine angle and the spine particularly around the cauda equina. Squash cytology finding of meningioma is well-established, however there is sparse literature available on squash cytology of CCM. Here we describe a case of CCM occurring in the lumbar spine in a young woman. Initially, on squash cytology a diagnosis of a low grade glioma favouring an ependymoma was considered. Eventually histopathological examination along with immunohistochemistry helped us reach the diagnosis of a CCM. In this article we discuss the cytomorphology of CCM along with its cytological differentials and the hurdles to an accurate diagnosis.
透明细胞脑膜瘤(CCM)是脑膜瘤的一种罕见组织学亚型。它通常位于小脑脑桥角和脊柱,特别是马尾周围。脑膜瘤的挤压细胞学发现已得到充分确立,但是关于 CCM 的挤压细胞学的文献很少。在这里,我们描述了一例发生在年轻女性腰椎的 CCM 病例。最初,在挤压细胞学上,考虑诊断为低度胶质瘤,倾向于室管膜瘤。最终,组织病理学检查和免疫组织化学检查帮助我们做出了 CCM 的诊断。在本文中,我们讨论了 CCM 的细胞形态学及其细胞学差异,并讨论了准确诊断的障碍。