Capino Amanda C, Miller Jamie L, Hughes Kaitlin M, Miller Michael J, Johnson Peter N
University of Oklahoma College of Pharmacy, Oklahoma City, OK, USA.
University of Michigan C. S. Mott Children's Hospital, Ann Arbor, MI, USA.
J Pharm Technol. 2016 Jun;32(3):104-115. doi: 10.1177/8755122515622030. Epub 2015 Dec 9.
There are no definitive guidelines regarding the management of iatrogenic opioid abstinence syndrome (IOAS), but methadone tapers are one common approach. Methadone tapers can be complex for caregivers to manage, and there is a paucity of data about caregiver experiences administering medication tapers postdischarge. The primary objective was to describe caregiver perception, self-efficacy, and knowledge of administering methadone tapers. Secondary objectives included an assessment of the change in self-efficacy and knowledge of methadone and IOAS before and after discharge as well as clinical outcomes occurring postdischarge. This was an exploratory, descriptive, institutional review board-approved study surveying caregivers of children receiving methadone tapers for IOAS. Caregivers were included if they had a child ≤12 years of age discharged to home on a methadone taper. The study consisted of 2 phases: a questionnaire and observation/counseling session predischarge and a telephone interview after taper completion. Univariate descriptive statistics were utilized for data analysis. Phase 1 of the study was completed by 12 caregivers, and only 5 completed phase 2. The majority of caregivers were completely confident predischarge (83.3%) and postdischarge (80%) in administering methadone as prescribed. However, some caregivers were confused about the purpose of the taper and experienced difficulty in measuring oral solutions. Despite high self-efficacy, caregivers experienced difficulties in understanding taper management and during the observation session. The results of this study suggest presenting information to caregivers utilizing minimal medical jargon, conducting a counseling/observation session predischarge, and utilizing the teach-back method with caregivers to assess for understanding.
关于医源性阿片类药物戒断综合征(IOAS)的管理,目前尚无明确的指导方针,但美沙酮递减疗法是一种常见的方法。美沙酮递减疗法对于护理人员来说管理起来可能很复杂,而且关于护理人员在出院后进行药物递减治疗的经验数据很少。主要目的是描述护理人员对美沙酮递减疗法的认知、自我效能感和给药知识。次要目的包括评估出院前后护理人员对美沙酮和IOAS的自我效能感和知识的变化,以及出院后的临床结果。这是一项经机构审查委员会批准的探索性、描述性研究,对接受美沙酮递减疗法治疗IOAS的儿童的护理人员进行调查。如果护理人员有一名12岁及以下的儿童在美沙酮递减疗法下出院回家,则将其纳入研究。该研究包括两个阶段:出院前的问卷调查和观察/咨询会议,以及递减疗法完成后的电话访谈。采用单变量描述性统计进行数据分析。研究的第一阶段有12名护理人员完成,只有5名完成了第二阶段。大多数护理人员在出院前(83.3%)和出院后(80%)对按处方服用美沙酮完全有信心。然而,一些护理人员对递减疗法的目的感到困惑,并且在测量口服溶液时遇到困难。尽管自我效能感很高,但护理人员在理解递减疗法管理方面以及观察期间仍遇到困难。这项研究的结果表明,应以最少的医学术语向护理人员提供信息,在出院前进行咨询/观察会议,并采用“反馈教学法”与护理人员评估其理解情况。