Barrett A P
J Periodontol. 1986 May;57(5):318-20. doi: 10.1902/jop.1986.57.5.318.
A case of severe oral ulceration, following administration of combination chemotherapy which included methotrexate, is reported. Topically applied folinic acid was effective in facilitating resolution of the oral lesions.
报告了1例在接受包括甲氨蝶呤在内的联合化疗后出现严重口腔溃疡的病例。局部应用亚叶酸有效地促进了口腔病变的消退。