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外科医生管理的腹横肌平面(TAP)阻滞与根治性膀胱切除术后阿片类药物使用减少和住院时间缩短相关。

Surgeon-administered Transversus Abdominis Plane (TAP) Block is Associated With Decreased Opioid Usage and Length of Stay Following Radical Cystectomy.

机构信息

Department of Urology, Carolinas Medical Center/Atrium Health, Charlotte, NC.

Department of Urology, University of Virginia, Charlottesville, VA.

出版信息

Urology. 2022 Mar;161:135-141. doi: 10.1016/j.urology.2021.11.023. Epub 2021 Dec 3.

DOI:10.1016/j.urology.2021.11.023
PMID:34864053
Abstract

OBJECTIVE

To study the effect of surgeon-administered Transversus Abdominis Plane block (sTAP) on opioid usage and length of stay (LOS).

METHODS

Starting in April 2018, two surgeons at our institution gradually introduced sTAP for radical cystectomy (RC) patients. We performed a retrospective observational cohort analysis of RC patients catalogued in a prospectively maintained database using the Enhanced Recovery After Surgery Interactive Auditing System. Two surgeons adopted the sTAP block technique in April 2018. We included patients undergoing RC for bladder malignancy under Enhanced Recovery After Surgery protocol between January 2017 and August 2020. Primary outcomes included LOS, and postoperative day (POD) 0-3 total opioids consumption measured by morphine milligram equivalents (MME). Multivariable linear or logistic models evaluated the association of TAP with outcomes while controlling for potential confounders.

RESULTS

Among 178 patients included in analysis, 84 patients underwent sTAP block and 94 did not. Multivariable analysis demonstrated significantly lower POD 0-3 total opioid usage (106.4 vs 192.2 MME, P = .004), and mean LOS (5.6 vs 7.7 days, P <.001) among the sTAP group.

CONCLUSION

sTAP appears to be an effective adjunct to RC care associated with improved LOS, and POD 0-3 opioid consumption. Further studies are needed to optimize TAP block technique and anesthetic composition.

摘要

目的

研究术者施行腹横肌平面阻滞(sTAP)对阿片类药物使用和住院时间(LOS)的影响。

方法

自 2018 年 4 月起,本机构的两位外科医生逐渐将 sTAP 用于根治性膀胱切除术(RC)患者。我们使用增强康复术后交互审核系统(Enhanced Recovery After Surgery Interactive Auditing System)对前瞻性维护数据库中的 RC 患者进行回顾性观察队列分析。两位外科医生于 2018 年 4 月采用 sTAP 阻滞技术。我们纳入了在增强康复术后方案下接受膀胱恶性肿瘤 RC 的患者。主要结局包括 LOS 和术后第 0-3 天(POD)的总阿片类药物消耗量,以吗啡毫克当量(MME)衡量。多变量线性或逻辑模型评估了 TAP 与结局的关联,同时控制了潜在的混杂因素。

结果

在纳入分析的 178 例患者中,84 例接受了 sTAP 阻滞,94 例未接受。多变量分析显示,sTAP 组术后第 0-3 天的总阿片类药物使用量(106.4 对 192.2 MME,P=0.004)和平均 LOS(5.6 对 7.7 天,P<0.001)明显更低。

结论

sTAP 似乎是 RC 护理的有效辅助手段,可改善 LOS 和术后第 0-3 天的阿片类药物消耗。需要进一步研究以优化 TAP 阻滞技术和麻醉成分。

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