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一名糖尿病患者发生由班替枝孢霉引起的复发性致命脑脓肿。

Recurrent fatal brain abscess by Cladophialophora bantiana in a diabetic patient.

作者信息

Gupta Parakriti, Kaur Harsimran, Mohindra Sandeep, Verma Shristi, Rudramurthy Shivaprakash

机构信息

Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Med Microbiol. 2022 Jan-Mar;40(1):152-155. doi: 10.1016/j.ijmmb.2021.11.011. Epub 2021 Dec 12.

Abstract

Cladophialophora bantiana is one of the significant causes of brain abscess in immunocompetent as well as immunocompromised individuals and accounts for a high level of mortality of 70%. The abscess can recur in immunocompromised patients, being managed conservatively with monotherapy and inadequate surgical debridement. The management of such cases is perplexing, posing an onerous challenge. This case underscores the snags encountered with monotherapy and the requisite for repeated surgical debridement and voriconazole in treatment regimen of complicated and recurrent cases.

摘要

班替枝孢霉是免疫功能正常和免疫功能低下个体脑脓肿的重要病因之一,死亡率高达70%。免疫功能低下患者的脓肿可能会复发,采用单一疗法和不充分的手术清创进行保守治疗。此类病例的治疗令人困惑,构成了一项艰巨的挑战。本病例强调了单一疗法所遇到的障碍以及在复杂和复发病例的治疗方案中重复进行手术清创和使用伏立康唑的必要性。

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