Shaw P J, Bates D, Cartlidge N E, French J M, Heaviside D, Julian D G, Shaw D A
Q J Med. 1986 Jan;58(225):59-68.
As part of a major prospective study of neurological and psychological complications of coronary artery bypass graft surgery, involving 312 patients, detailed psychometric testing was carried out before and after operation on 298 patients using a battery of 10 standard tests of intellectual function. This report is concerned with the early neuropsychological dysfunction detectable one week after operation. Two hundred and thirty-five patients (79 per cent of the cohort) showed impairment in some aspect of cognitive function at the seventh day after operation. Only 63 patients (21 per cent) showed no deterioration from levels before operation in any of the 10 test scores. One hundred and twenty-three of the patients whose scores deteriorated had no symptoms while in hospital. Eighty-nine patients complained of cognitive impairment, and 23 patients were considered to be overtly disabled by their intellectual dysfunction, during the period soon after operation. There is therefore a high incidence of early cerebral dysfunction detectable by psychometric testing following coronary artery bypass graft surgery. Often this was not of sufficient severity to cause serious concern to the patients or to interfere with their everyday activities in the hospital environment.
作为一项针对冠状动脉搭桥手术神经和心理并发症的大型前瞻性研究的一部分，该研究涉及312名患者，对其中298名患者在手术前后使用一组10项标准智力功能测试进行了详细的心理测量测试。本报告关注术后一周可检测到的早期神经心理功能障碍。235名患者（占队列的79%）在术后第7天出现了认知功能某些方面的损害。只有63名患者（21%）在10项测试分数中的任何一项上与术前水平相比没有恶化。分数恶化的患者中有123人在住院期间没有症状。89名患者抱怨有认知障碍，23名患者在术后不久被认为因智力功能障碍而明显残疾。因此，冠状动脉搭桥手术后通过心理测量测试可检测到早期脑功能障碍的发生率很高。通常，其严重程度不足以引起患者的严重关注或干扰他们在医院环境中的日常活动。
