Maciejewski W, Wolff H H, Schmoeckel C
Hautarzt. 1978 Apr;29(4):183-90.
The principle of immunoelectronmicroscopic studies using horseradish perpoxidase is described. This method, especially the peroxidase-antiperoxidase multistep technique, reveals more details about the exact localization of immunophenomena in different dermatological diseases. The results of immunological investigations performed on the ultra-structural level in bullous diseases, lupus erythermatosus, vasculitis, and psoriasis are summarized and compared with the immunofluorescent and classical electromicroscopic findings.
本文描述了使用辣根过氧化物酶进行免疫电子显微镜研究的原理。这种方法,尤其是过氧化物酶-抗过氧化物酶多步技术,揭示了不同皮肤病中免疫现象确切定位的更多细节。总结了在大疱性疾病、红斑狼疮、血管炎和银屑病的超微结构水平上进行的免疫学研究结果,并与免疫荧光和经典电子显微镜检查结果进行了比较。