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冠状动脉搭桥术后新发束支传导阻滞的病因及临床意义。

Etiology and clinical significance of new fascicular conduction defects following coronary bypass surgery.

作者信息

Wexelman W, Lichstein E, Cunningham J N, Hollander G, Greengart A, Shani J

出版信息

Am Heart J. 1986 May;111(5):923-7. doi: 10.1016/0002-8703(86)90643-5.

Abstract

Two hundred consecutive patients undergoing only coronary bypass surgery were studied. Forty-five patients (group A) developed new fascicular conduction blocks and 155 patients (group B) did not. The 45 patients in group A developed the following fascicular conduction blocks: right bundle branch block 47%, right bundle branch block and left anterior hemiblock 8%, right bundle branch block and first-degree atrioventricular block 2%, left anterior hemiblock 11%, left bundle branch block 18%, right bundle branch block-left anterior hemiblock and first-degree atrioventricular block 5%. There were no significant differences in sex, incidence of diabetes, number of grafts performed, ejection fraction (less than 55%), and perioperative infarction. Group A patients were older (p less than 0.01). Hypertension was found frequently in group A (27 vs 45 patients; p less than 0.01) and was present for a mean of 12.4 years in group A and 4.9 years in group B (p less than 0.01). Preoperative use of digitalis was found in 14 (31%) patients in group A and in 18 (12%) patients in group B (p less than 0.01). Twenty-one (47%) patients in group A had significant disease (greater than 70%) of the left main coronary artery as compared to 17 (10.9%) in group B (p less than 0.001). There was no difference in the recurrence of angina or the survival rate at 14 months. In conclusion, the incidence of new fascicular conduction block after bypass surgery is 22.5%. Long-standing hypertension, left main coronary disease, and the preoperative use of digitalis appear to be predisposing factors. New fascicular conduction block does not affect prognosis.

摘要

对仅接受冠状动脉搭桥手术的200例连续患者进行了研究。45例患者(A组)出现了新的束支传导阻滞,155例患者(B组)未出现。A组的45例患者出现了以下束支传导阻滞:右束支传导阻滞47%,右束支传导阻滞合并左前分支阻滞8%,右束支传导阻滞合并一度房室传导阻滞2%,左前分支阻滞11%,左束支传导阻滞18%,右束支传导阻滞-左前分支阻滞合并一度房室传导阻滞5%。在性别、糖尿病发病率、移植血管数量、射血分数(小于55%)和围手术期梗死方面无显著差异。A组患者年龄较大(p<0.01)。A组高血压的发生率较高(27例对45例患者;p<0.01),A组高血压平均存在12.4年,B组为4.9年(p<0.01)。A组14例(31%)患者术前使用洋地黄,B组18例(12%)患者术前使用洋地黄(p<0.01)。A组21例(47%)患者左主冠状动脉病变严重(>70%),而B组为17例(10.9%)(p<0.001)。在14个月时,心绞痛复发率或生存率无差异。总之,搭桥手术后新的束支传导阻滞发生率为22.5%。长期高血压、左主冠状动脉疾病和术前使用洋地黄似乎是易感因素。新的束支传导阻滞不影响预后。

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