Zeldis S M, Morganroth J, Horowitz L N, Michelson E L, Josephson M E, Lozner E C, MacVaugh H, Kastor J A
Am J Cardiol. 1978 May 1;41(5):860-4. doi: 10.1016/0002-9149(78)90725-7.
Two hundred patients underogoing coronary bypass graft surgery were studied to determine the frequency and significance fo new fascicular conduction distrubances. The follow-up period ranged from 13 to 39 months. New disturbances developed in 39 patients (20 percent). Isolated right bundle branch block (6 percent) and left anterior hemiblock (6 percent) were the most common disturbances. Righ bundle branch block was usually transient and was not associated with further complications in the follow-up period. However, patients with either transient or persistent left bundle branch block or left anterior hemiblock, or both, had (1) increased later mortality compared with patients without new fascicular conduction disturbances (5 of 26 versus 11 of 161; P less than 0.02), and (2) increased late myocardial infarction (2 of 26 versus 2 of 161; P less than 0.05). New left fascicular conduction disturbances after coronary surgery identified a subset of patients with more extensive ischemic heart disease, suggesting that these patients require close follow-up care.
对200例行冠状动脉搭桥手术的患者进行研究,以确定新的束支传导障碍的发生率及其意义。随访期为13至39个月。39例患者(20%)出现了新的障碍。孤立性右束支传导阻滞(6%)和左前分支阻滞(6%)是最常见的障碍。右束支传导阻滞通常是短暂的,在随访期内未出现进一步并发症。然而,出现短暂或持续性左束支传导阻滞或左前分支阻滞,或两者皆有的患者,(1)与无新束支传导障碍的患者相比,后期死亡率增加(26例中有5例,而161例中有11例;P<0.02),(2)后期心肌梗死发生率增加(26例中有2例,而161例中有2例;P<0.05)。冠状动脉手术后新出现的左束支传导障碍确定了一组患有更广泛缺血性心脏病的患者,提示这些患者需要密切的随访护理。