Horton Jonathan C, Adams Daniel L, Economides John R
Department of Ophthalmology, Program in Neuroscience, University of California, San Francisco.
Shinkei Ganka. 2020 Jun 25;37(2):196-202. doi: 10.11476/shinkeiganka.37.196. Epub 2020 Jul 8.
Patient with exotropia frequently alternate fixation, looking at something with one eye and then switching their attention to acquire a new target with the other eye. Which eye informs the brain about the location of the new target? To address this issue, we presented targets dichoptically to 16 exotropes that were visible to the fixating eye, the deviated eye, or to both eyes. We then compared the subjects' choice of eye for target acquisition with the organization of their suppression scotomas. There was a correspondence between suppression scotoma maps and the eye used to acquire peripheral targets. In other words, a target perceived via an eye was also fixated by it. These studies reveal how patients with alternating strabismus, despite eye misalignment, manage to localize and fixate efficiently visual targets in their environment.
外斜视患者经常交替注视，先用一只眼睛看某个东西，然后将注意力转移到另一只眼睛以获取新目标。哪只眼睛会将新目标的位置信息传递给大脑呢？为了解决这个问题，我们将目标以双眼分视的方式呈现给16名外斜视患者，这些目标对注视眼、偏斜眼或双眼都是可见的。然后，我们将受试者获取目标时眼睛的选择与其抑制性暗点的分布进行了比较。抑制性暗点图与用于获取周边目标的眼睛之间存在对应关系。换句话说，通过某只眼睛感知到的目标也会被该只眼睛注视。这些研究揭示了交替性斜视患者尽管存在眼球偏斜，但仍能在其环境中有效地定位和注视视觉目标的方式。
