Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
Annu Rev Neurosci. 2011;34:205-31. doi: 10.1146/annurev-neuro-061010-113728.
The mammalian superior colliculus (SC) and its nonmammalian homolog, the optic tectum, constitute a major node in processing sensory information, incorporating cognitive factors, and issuing motor commands. The resulting action-to orient toward or away from a stimulus-can be accomplished as an integrated movement across oculomotor, cephalomotor, and skeletomotor effectors. The SC also participates in preserving fixation during intersaccadic intervals. This review highlights the repertoire of movements attributed to SC function and analyzes the significance of results obtained from causality-based experiments (microstimulation and inactivation). The mechanisms potentially used to decode the population activity in the SC into an appropriate movement command are also discussed.
哺乳动物的上丘（SC）及其非哺乳动物同源物，视顶盖，构成了处理感觉信息的主要节点，包含认知因素，并发出运动命令。由此产生的朝向或远离刺激的动作可以作为眼球运动、头运动和骨骼运动效应器的综合运动来完成。SC 还参与在眼跳间隔期间保持注视。本综述强调了归因于 SC 功能的运动范围，并分析了基于因果关系的实验（微刺激和失活）获得的结果的意义。还讨论了潜在用于将 SC 中的群体活动解码为适当运动命令的机制。
