Dégboé Bérénice, Atadokpèdé Félix, Nguessie Christabelle, Kouassi Alida, Elégbédé Nadège, Maffo Nina, Akpadjan Fabrice, Adégbidi Hugues
Department of Dermatology Venereology, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Faculty of Health Sciences, University of Abomey-Calavi, Godomey, Benin.
Dermatol Res Pract. 2021 Nov 24;2021:1502721. doi: 10.1155/2021/1502721. eCollection 2021.
The objective of this work was to document the comorbidities and environmental factors associated with atopic dermatitis (AD) in dermatology Venereology in Cotonou.
A cross-sectional, prospective, and analytical study included, from January 2016 to December 2018, in the Dermatology-Venereology Department of the National Teaching Hospital Hubert Koutoukou Maga (CNHU-HKM) of Cotonou, children and adults after free and informed consent, in whom the diagnosis of AD was retained according to the criteria of the United Kingdom Working Party. Severity was assessed using SCORAD (severity scoring of atopic dermatitis).
The overall prevalence of AD was 7.7%. AD was more frequent in children (56.8% and 40.6%) and adults (59.8% and 37.4%) from urban and periurban areas (0.003 < < 0.034). It was more frequent in children who regularly dewormed and those with complete vaccination (0.001 < < 0.01). In 54.8% of children and 58.9% of adults, flare-ups occurred during the warm season. The main associated comorbidities were rhinitis and conjunctivitis in both children (49.7% and 36.1%, respectively) and adults (32.7% and 26.2%, respectively). The main triggering factors in children were heat (43.2%), pneumallergens (28.4%), and skin irritants (22.6%). In adults, we noted skin irritants (58.9%), heat (47.7%), and psychological factors (34.6%). In adults, the use of detergent soaps was associated with lichenified and severe AD (0.003 < < 0.006) and that of lightening soaps with acute AD (=0.042).
AD in the Dermatology-Venereology Department of the CNHU-HKM of Cotonou was associated with comorbidities. It was influenced by environmental factors related to the tropical climate and by skin irritants or allergens.
本研究的目的是记录科托努皮肤病与性病科中与特应性皮炎（AD）相关的合并症和环境因素。
一项横断面、前瞻性分析研究于2016年1月至2018年12月在科托努国家教学医院于贝尔·库图库·马加（CNHU-HKM）的皮肤病与性病科开展，纳入了获得自由且知情同意的儿童和成人，这些患者根据英国工作组的标准被确诊为AD。使用SCORAD（特应性皮炎严重程度评分）评估病情严重程度。
AD的总体患病率为7.7%。城市和城郊地区的儿童（56.8%和40.6%）及成人（59.8%和37.4%）中AD更为常见（0.003＜ ＜0.034）。在定期驱虫和完成疫苗接种的儿童中更为常见（0.001＜ ＜0.01）。54.8%的儿童和58.9%的成人在温暖季节病情加重。主要的相关合并症在儿童和成人中均为鼻炎和结膜炎（分别为49.7%和36.1%，以及32.7%和26.2%）。儿童的主要诱发因素为炎热（43.2%）、气源性变应原（28.4%）和皮肤刺激物（22.6%）。在成人中，我们注意到皮肤刺激物（58.9%）、炎热（47.7%）和心理因素（34.6%）。在成人中，使用去污皂与苔藓化和重度AD相关（0.003＜ ＜0.006），而使用美白皂与急性AD相关（=0.042）。
科托努CNHU-HKM皮肤病与性病科的AD与合并症相关。它受到与热带气候相关的环境因素以及皮肤刺激物或变应原的影响。
