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1例在Ga-DOTATOC PET/CT上表现为酷似神经内分泌肿瘤的血管球瘤病例。

A Case of Glomus Tumor Mimicking Neuroendocrine Tumor on  Ga-DOTATOC PET/CT.

作者信息

Lee Koeun, Ahn Bokyung, Hong Seung-Mo, Ahn Ji Yong, Gong Chung Sik, Ryu Jin-Sook

机构信息

Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505 Republic of Korea.

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

出版信息

Nucl Med Mol Imaging. 2021 Dec;55(6):315-319. doi: 10.1007/s13139-021-00717-3. Epub 2021 Oct 13.

DOI:10.1007/s13139-021-00717-3
PMID:34868381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8602595/
Abstract

Ga-DOTA-peptide PET/CT is a valuable tool for diagnosing neuroendocrine tumors (NET). Various tumors and normal human tissue express the somatostatin receptor (SSTR), warranting attention to positive findings on  Ga-DOTA-peptide PET/CT. However, overexpression of SSTR in glomus tumors has not yet been reported. Gastric glomus tumors show many similar features of NET and are often misdiagnosed. We present the case of a 61-year-old male with a glomus tumor who underwent distal gastrectomy under the pretense of an NET grade 1 because the nodule showed focal intense uptake on preoperative  Ga-DOTATOC PET/CT.

摘要

镓标记的DOTA肽PET/CT是诊断神经内分泌肿瘤(NET)的一种有价值的工具。各种肿瘤和正常人体组织均表达生长抑素受体(SSTR),因此镓标记的DOTA肽PET/CT上的阳性结果值得关注。然而,尚未有文献报道血管球瘤中SSTR的过表达情况。胃血管球瘤表现出许多与NET相似的特征,常被误诊。我们报告了一例61岁患有血管球瘤的男性病例,该患者因术前镓标记的DOTA-TOC PET/CT显示结节有局灶性强烈摄取,在疑似1级NET的情况下接受了远端胃切除术。