Maslov Diana V, Badari Ambuga
Ochsner Clinic Foundation, Department of Internal Medicine, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
The Gayle and Tom Benson Cancer Center, 1516 Jefferson Highway, Jefferson LA 70121, USA.
Case Rep Oncol Med. 2021 Nov 25;2021:9953230. doi: 10.1155/2021/9953230. eCollection 2021.
Acute lymphoblastic leukemia (ALL) is a neoplasm of the B cell or T cell. Diagnosis is made by peripheral blood smear and bone marrow biopsy. Those with relapse/measurable residual disease (MRD) present with fever, weakness, fatigue, and easy bruising due to bone marrow infiltration (Kantarjian et al., 2017). A 59-year-old male with history of relapsed acute lymphoblastic leukemia and allogeneic stem cell transplant presented to the Emergency Department (ED) multiple times with shortness of breath. 2D Echo revealed recurrent pericardial effusion. His MRD was discovered in the pericardium. He underwent the creation of a pericardial window with cytology and culture which confirmed B cell lymphoblastic leukemia/lymphoma, consistent with relapsed disease. We present a case of a patient with B-ALL and MRD who presented with symptoms of shortness of breath. His MRD was discovered not in the bone marrow, but in the pericardium.
急性淋巴细胞白血病（ALL）是一种B细胞或T细胞的肿瘤。通过外周血涂片和骨髓活检进行诊断。那些复发/可测量残留疾病（MRD）的患者由于骨髓浸润而出现发热、虚弱、疲劳和容易瘀伤（坎塔尔坚等人，2017年）。一名有复发急性淋巴细胞白血病和异基因干细胞移植病史的59岁男性多次因呼吸急促就诊于急诊科（ED）。二维超声心动图显示复发性心包积液。在他的心包中发现了MRD。他接受了心包开窗术并进行了细胞学和培养，结果证实为B细胞淋巴细胞白血病/淋巴瘤，与复发疾病一致。我们报告一例患有B-ALL和MRD且出现呼吸急促症状的患者。他的MRD不是在骨髓中发现的，而是在心包中发现的。
