Zhang Zhe, Niu Lingling, Zhao Jing, Miao Huamao, Chen Zhuoyi, Shen Yang, Chen Xun, Ye Yuhao, Wang Xiaoying, Zhou Xingtao
Department of Ophthalmology, Eye Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.
NHC Key Laboratory of Myopia, Fudan University, Shanghai, China.
Front Med (Lausanne). 2021 Nov 17;8:764653. doi: 10.3389/fmed.2021.764653. eCollection 2021.
To compare the safety of the non-ophthalmic viscosurgical device (OVD) technique with that of the minimum OVD technique in EVO Implantable Collamer Lens (EVO-ICL) implantation. A total of 180 eyes of 90 consecutive patients were enrolled in the study, of which 100 eyes of 50 patients were treated with non-OVD technique, with a 55% success rate. The remaining 80 eyes of 40 patients were treated with min-OVD technique, so they were classified into the min-OVD group. Preoperative and postoperative intraocular pressure (IOP) measurements were collected and analyzed at 1, 2, 3, and 24 h. Visual acuity, corneal endothelial cell density (ECD), and corneal densitometry 24 h postoperatively were evaluated. No significant difference was found in visual outcomes ( = 0.54) or ECD ( = 0.78) between the two groups. The operation time was significantly shorter in the non-OVD group ( < 0.0001). The IOP was significantly higher at 1 h ( < 0.0001), 2 h ( < 0.0001) and 3 h ( = 0.0045) postoperatively in the min-OVD group. The non-OVD group had significantly lower IOP than the min-OVD group at 1 h ( = 0.01) and 2 h ( = 0.013) postoperatively. The temporal corneal densitometry in the non-OVD group were significantly lower than those in the minimum group ( = 0.0063) 1 day after surgery. The non-OVD technique is safe and efficient for ICL implantation. It can be a safer method of ICL implantation in that it completely eliminates ophthalmic viscoelastic devices related complications without causing additional complications in short term.
比较非眼科粘弹剂(OVD)技术与最小量OVD技术在EVO可植入式角膜接触镜(EVO-ICL)植入术中的安全性。该研究共纳入90例连续患者的180只眼,其中50例患者的100只眼采用非OVD技术治疗,成功率为55%。其余40例患者的80只眼采用最小量OVD技术治疗,因此被归入最小量OVD组。收集并分析术前及术后1、2、3和24小时的眼压(IOP)测量值。评估术后24小时的视力、角膜内皮细胞密度(ECD)和角膜密度。两组之间在视觉结果(P = 0.54)或ECD(P = 0.78)方面未发现显著差异。非OVD组的手术时间明显更短(P < 0.0001)。最小量OVD组术后1小时(P < 0.0001)、2小时(P < 0.0001)和3小时(P = 0.0045)的IOP明显更高。非OVD组术后1小时(P = 0.01)和2小时(P = 0.013)的IOP明显低于最小量OVD组。术后1天,非OVD组颞侧角膜密度明显低于最小量OVD组(P = 0.0063)。非OVD技术用于ICL植入安全且有效。它可能是一种更安全的ICL植入方法,因为它完全消除了与眼科粘弹剂相关的并发症,且短期内不会引起额外并发症。