Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Ophthalmology, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai, China.
Indian J Ophthalmol. 2024 Sep 1;72(9):1291-1297. doi: 10.4103/IJO.IJO_2859_23. Epub 2024 May 20.
To investigate the efficacy and safety of a modified dual-incision ophthalmic viscosurgical device-free (OVD-free) method for implantable collamer lens (ICL) implantation in high myopic eyes.
A total of 68 participants were enrolled in this prospective randomized clinical trial, including 33 in the OVD-free group and 35 in the standard group. Operation time and intraocular pressure (IOP) at 2 hours postoperatively were recorded. Visual acuity, refractive power, IOP, corneal endothelium parameters, and anterior segment parameters were assessed at 1 day, 1 week, 1 month, 3 months, and 6 months postoperatively. Postoperative subjective visual quality at 3 months was recorded through a Quality of Vision (QoV) questionnaire.
No significant differences in visual acuity, refractive outcomes, and corneal endothelial parameters were found, while the operation time was significantly shorter in the OVD-free group. Both groups showed a significant increase in IOP at 2 hours after surgery, but the increase in the OVD-free group was significantly smaller than that in the standard group. In addition, the frequency of ring-shaped dysphotopsia in the OVD-free group (15.15%) was significantly lower than that in the standard group (40%), and the severity and annoyance of this symptom were also significantly lower in the OVD-free group.
The modified OVD-free ICL implantation is a safe, effective, and predictable method for myopia correction, which could be a better choice for short surgery time, better subjective visual perception, and low occurrence of IOP elevation.
研究改良免粘弹剂的双切口白内障超声乳化吸除术中人工晶状体（ICL）植入术治疗高度近视的疗效和安全性。
前瞻性随机临床试验纳入 68 例患者，其中 33 例为免粘弹剂组，35 例为标准组。记录手术时间和术后 2 小时眼压。术后 1 天、1 周、1 个月、3 个月和 6 个月评估视力、屈光力、眼压、角膜内皮细胞参数和眼前段参数。术后 3 个月通过视觉质量问卷（QoV）记录术后主观视觉质量。
免粘弹剂组与标准组之间视力、屈光结果和角膜内皮细胞参数无显著差异，但手术时间显著缩短。两组术后 2 小时眼压均显著升高，但免粘弹剂组眼压升高幅度明显小于标准组。此外，免粘弹剂组环形炫光的发生率（15.15%）明显低于标准组（40%），且免粘弹剂组的症状严重程度和烦恼程度也明显低于标准组。
改良免粘弹剂的 ICL 植入术是一种安全、有效、可预测的治疗近视的方法，对于手术时间短、主观视觉感知更好、眼压升高发生率低的患者来说，可能是更好的选择。
