Palmas C, Bortoletti G, Conchedda M, Gabriele F
Z Parasitenkd. 1986;72(3):397-403. doi: 10.1007/BF00928750.
The presence of small cells carrying memory and lymphoblast migration in C57 Bl/6N inbred mice with the intestinal parasite Hymenolepis nana were investigated. Hymenolepis nana egg-infection stimulated an enhanced accumulation of mesenteric lymphoblasts at days 3, 6 and 9 after infection; lymphoblasts accumulated selectively in the mesenteric nodes (MLN) of mice suggesting a cell-trapping effect. The migration was studied using lymphoblasts from non-infected donors. Spleen cells and MLNC collected from donor mice 30 days after a primary infection and enriched for T cells were able to transfer an adoptive immunity, by contrast unseparated cells were uneffective. This result provides preliminary evidence for the existence of T memory cells in the spleen and in the mesenteric nodes.
研究了感染肠道寄生虫微小膜壳绦虫的C57 Bl/6N近交系小鼠中携带记忆和淋巴细胞迁移的小细胞的存在情况。微小膜壳绦虫卵感染在感染后第3、6和9天刺激肠系膜淋巴细胞的积累增强；淋巴细胞选择性地在小鼠的肠系膜淋巴结（MLN）中积累，提示有细胞捕获效应。使用来自未感染供体的淋巴细胞研究迁移情况。初次感染30天后从供体小鼠收集的脾细胞和MLNC并富集T细胞能够传递过继免疫，相比之下，未分离的细胞则无效。这一结果为脾脏和肠系膜淋巴结中存在T记忆细胞提供了初步证据。
