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一种基于双模式增强现实的神经内镜导航系统用于高血压性脑出血的微创外科治疗。

A neuroendoscopic navigation system based on dual-mode augmented reality for minimally invasive surgical treatment of hypertensive intracerebral hemorrhage.

作者信息

Zhu Tao, Jiang Shan, Yang Zhiyong, Zhou Zeyang, Li Yuhua, Ma Shixing, Zhuo Jie

机构信息

School of Mechanical Engineering, Tianjin University, Tianjin, 300350, China.

School of Mechanical Engineering, Tianjin University, Tianjin, 300350, China.

出版信息

Comput Biol Med. 2022 Jan;140:105091. doi: 10.1016/j.compbiomed.2021.105091. Epub 2021 Nov 29.

Abstract

BACKGROUND AND OBJECTIVE

Hypertensive intracerebral hemorrhage is characterized by a high rate of morbidity, mortality, disability and recurrence. Neuroendoscopy has been utilized for treatment as an advanced technology. However, traditional neuroendoscopy allows professionals to see only tissue surfaces, and the field of vision is limited, which cannot provide spatial guidance. In this study, an AR-based neuroendoscopic navigation system is proposed to assist surgeons in locating and clearing hematoma.

METHODS

The neuroendoscope can be registered through the vector closed loop algorithm. The single-shot method is designed to register medical images with patients precisely. Real-time AR is realized based on video stream fusion. Dual-mode AR navigation is proposed to provide comprehensive guidance from catheter implantation to hematoma removal. A series of experiments is designed to validate the accuracy and significance of this system.

RESULTS

The average root mean square error of the registration between medical images and patients is 0.784 mm, and the variance is 0.1426 mm. The pixel mismatching degrees are less than 1% in different AR modes. In catheter implantation experiments, the average error of distance is 1.28 mm, and the variance is 0.43 mm, while the average error of angles is 1.34°, and the variance is 0.45°. Comparative experiments are also conducted to evaluate the feasibility of this system.

CONCLUSION

This system can provide stereo images with depth information fused with patients to guide surgeons to locate targets and remove hematoma. It has been validated to have high accuracy and feasibility.

摘要

背景与目的

高血压性脑出血具有高发病率、高死亡率、高致残率及高复发率的特点。神经内镜作为一项先进技术已被用于治疗。然而,传统神经内镜只能让专业人员看到组织表面,视野有限,无法提供空间引导。本研究提出一种基于增强现实(AR)的神经内镜导航系统,以辅助外科医生定位和清除血肿。

方法

通过矢量闭环算法对神经内镜进行配准。设计单次方法将医学图像与患者精确配准。基于视频流融合实现实时AR。提出双模式AR导航,从导管植入到血肿清除提供全面引导。设计一系列实验验证该系统的准确性和有效性。

结果

医学图像与患者配准的平均均方根误差为0.784毫米,方差为0.1426毫米。在不同AR模式下像素错配度小于1%。在导管植入实验中,距离平均误差为1.28毫米,方差为0.43毫米,角度平均误差为1.34°,方差为0.45°。还进行了对比实验以评估该系统的可行性。

结论

该系统可提供融合患者的带有深度信息的立体图像,以引导外科医生定位目标并清除血肿。已验证其具有高准确性和可行性。

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