Brigham and Women's Hospital, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.
Hand (N Y). 2023 May;18(3):401-406. doi: 10.1177/15589447211058821. Epub 2021 Dec 7.
The outcomes of cubital tunnel syndrome surgery are affected by preoperative disease severity. The aim of this study was to identify factors associated with clinical and electrodiagnostic severity of cubital tunnel syndrome at presentation.
We retrospectively identified 213 patients with electrodiagnostically confirmed cubital tunnel syndrome who underwent cubital tunnel surgery from July 2008 to June 2013. Our primary response variable was clinical cubital tunnel syndrome severity assessed by the McGowan grade. Our secondary response variables were sensory nerve action potential (SNAP) recordability, presence of fibrillations, and motor nerve conduction velocities (CVs) in the abductor digiti minimi (ADM) and first dorsal interosseous (FDI). Bivariate analysis was used to screen for factors associated with disease severity; significant variables were selected for multivariable regression analysis.
Older age was associated with higher McGowan grade and diabetes mellitus was associated with unrecordable SNAPs on bivariate analysis. No other variables met inclusion criteria for multivariable regression analysis for McGowan grade or unrecordable SNAPs. Multivariable regression analysis showed older age and higher Distressed Communities Index (DCI) to be associated with decreased motor nerve CVs in ADM. Multivariable regression analysis showed higher body mass index (BMI) and higher DCI to be associated with decreased motor nerve CVs in FDI. No variable was associated with the presence of fibrillations.
A subset of patients with cubital tunnel syndrome may benefit from earlier referral for hand surgery evaluation and earlier surgery. Older patients, with higher BMI, with diabetes mellitus, and with economic distress are at higher risk for presentation with more severe disease.
肘管综合征手术的结果受术前疾病严重程度的影响。本研究旨在确定与肘管综合征发病时临床和电诊断严重程度相关的因素。
我们回顾性地确定了 213 例经电诊断证实的肘管综合征患者,他们在 2008 年 7 月至 2013 年 6 月期间接受了肘管松解术。我们的主要反应变量是由 McGowan 分级评估的临床肘管综合征严重程度。我们的次要反应变量是感觉神经动作电位 (SNAP) 的可记录性、纤颤的存在以及小指展肌(ADM)和第一骨间背侧肌(FDI)的运动神经传导速度 (CV)。使用二变量分析筛选与疾病严重程度相关的因素;对有意义的变量进行多变量回归分析。
年龄较大与较高的 McGowan 分级相关,糖尿病与 SNAP 不可记录相关。在二变量分析中,没有其他变量符合 McGowan 分级或 SNAP 不可记录的多变量回归分析的纳入标准。多变量回归分析显示,年龄较大和较高的困扰社区指数(DCI)与 ADM 运动神经 CV 降低相关。多变量回归分析显示,较高的 BMI 和较高的 DCI 与 FDI 运动神经 CV 降低相关。没有变量与纤颤的存在相关。
一部分肘管综合征患者可能需要更早地转介进行手部手术评估和更早地手术。年龄较大、BMI 较高、患有糖尿病和经济困难的患者,其疾病严重程度更高的风险更高。