Department of Psychiatry, the Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
Department of Psychiatry, the Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
Arch Gerontol Geriatr. 2018 Mar-Apr;75:70-75. doi: 10.1016/j.archger.2017.11.003. Epub 2017 Nov 20.
Prevalence of mild cognitive impairment (MCI) has been reported substantial variations, and mostly in Western countries. Less is known about MCI in the south of China. The study is to estimate the prevalence of MCI and its subtypes in residents aged 65year or older in community-dwelling residents of Guangzhou, China.
The study was a community-based, cross-sectional study conducted in rural and urban areas of Guangzhou between April and October 2009. Eight communities were randomly selected using a cluster sampling method. Each elderly was interviewed with Montreal Cognitive Assessment, the Mini-Mental state examination, Auditory Verbal Learning Test, the Clinical Dementia Rating scale et al. MCI was classified as amnestic MCI (a-MCI) or nonamnestic MCI (na-MCI).
2427 individuals were contacted, but in-person interviews were conducted with 2111 participants. 299 participants with MCI were identified. The prevalence of MCI, a-MCI and na-MCI was 14.2%, 12.2%, 2.0% respectively. The prevalence of MCI and a-MCI increased with age, decreased with education level, and was higher in rural areas than in urban areas. The difference of prevalence of MCI and a-MCI between women with men wasn't statistically significant(MCIχ2=1.0, OR 0.9, 95%CI=0.6-1.2; a-MCIχ2=1.0, OR 0.9, 95%CI=0.6-1.2), when controlling for education by logistic regression analysis.
The results suggest that 14.2% of elderly individuals are affected by MCI in Guangzhou, China. And MCI was dominated by a-MCI. The prevalence of MCI and a-MCI increased with age, decreased with education level, and was higher in the rural population compared to the urban population.
轻度认知障碍（MCI）的患病率在不同国家报道存在很大差异，且大多集中在西方国家。中国南方地区 MCI 的相关研究较少。本研究旨在评估中国广州社区老年人 MCI 及其亚型的患病率。
本研究为 2009 年 4 月至 10 月在中国广州城乡社区进行的基于人群的横断面研究。采用整群抽样方法随机选择 8 个社区。每位老年人均采用蒙特利尔认知评估、简易精神状态检查、听觉词语学习测验、临床痴呆评定量表等进行评估。MCI 分为遗忘型 MCI（a-MCI）和非遗忘型 MCI（na-MCI）。
共接触 2427 人，对 2111 人进行了面对面访谈。共确诊 MCI 患者 299 例。MCI、a-MCI 和 na-MCI 的患病率分别为 14.2%、12.2%和 2.0%。MCI 和 a-MCI 的患病率随年龄增长而增加，随教育程度降低而降低，农村地区高于城市地区。多因素逻辑回归分析显示，女性与男性 MCI 和 a-MCI 的患病率差异无统计学意义（MCI χ2=1.0，OR 0.9，95%CI=0.61.2；a-MCI χ2=1.0，OR 0.9，95%CI=0.61.2）。
广州地区 14.2%的老年人患有 MCI，以 a-MCI 为主。MCI 和 a-MCI 的患病率随年龄增长而增加，随教育程度降低而降低，农村地区高于城市地区。
