Division of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Department of Emergency Medicine, Local Health Care Services in Central Östergötland, Linköping, Sweden.
J Biophotonics. 2022 Apr;15(4):e202100270. doi: 10.1002/jbio.202100270. Epub 2022 Feb 12.
Monitoring of respiration is a central task in clinical medicine, crucial to patient safety. Despite the uncontroversial role of altered respiratory frequency as an important sign of impending or manifest deterioration, reliable measurement methods are mostly lacking outside of intensive care units and operating theaters. Photoplethysmography targeting the central blood circulation in the sternum could offer accurate and inexpensive monitoring of respiration. Changes in blood flow related to the different parts of the respiratory cycle are used to identify the respiratory pattern. The aim of this observational study was to compare photoplethysmography at the sternum to standard capnography in healthy volunteers. Bland Altman analysis showed good agreement (bias -0.21, SD 1.6, 95% limits of agreement -3.4 to 2.9) in respiratory rate values. Photoplethysmography provided high-quality measurements of respiratory rate comparable to capnographic measurements. This suggests that photoplethysmography may become a precise, cost-effective alternative for respiratory monitoring.
呼吸监测是临床医学中的一项核心任务，对患者安全至关重要。尽管呼吸频率的改变作为即将发生或明显恶化的重要标志是无可争议的，但除了重症监护病房和手术室之外，可靠的测量方法大多缺乏。针对胸骨中央血液循环的光体积描记术可以提供准确且经济实惠的呼吸监测。与呼吸周期不同部分相关的血流变化用于识别呼吸模式。这项观察性研究的目的是将胸骨处的光体积描记术与健康志愿者的标准二氧化碳描记术进行比较。Bland–Altman 分析显示，呼吸频率值的一致性良好（偏差-0.21，标准差 1.6，95%一致性界限-3.4 至 2.9）。光体积描记术提供了高质量的呼吸率测量值，与二氧化碳描记术测量值相当。这表明光体积描记术可能成为一种精确、具有成本效益的呼吸监测替代方法。
