Lembcke B, Schneider H, Lankisch P G
Endoscopy. 1986 May;18(3):80-3. doi: 10.1055/s-2007-1018336.
This retrospective, controlled study covers data from the medical records of 298 hospitalized patients, who, during the period 1972-1982, had 1,007 hydraulic small bowel biopsies removed on 342 occasions. The main complication was hemorrhage (drop in hemoglobin concentration greater than or equal to 2 g/100 ml) in 1.5% of the investigations. In one case (0.3%) transfusions were required. One other patient (0.3%) needed laparotomy following perforation. No deaths due to jejunal biopsy were observed in our series. Four patients (1.2%) developed transient temperature greater than or equal to 38 degrees C in response to the biopsy. The final diagnosis 'small bowel bacterial overgrowth' in three of these patients suggests that bacteremia was the cause of postbiopsy fever, and that bacterial overgrowth predisposes to this complication of jejunal biopsy. Neither the number of biopsies (n = 1-20), nor the performance of repeat investigations in the same patient, nor the year of investigation, nor nutritional status showed any correlation to the development of complications.
这项回顾性对照研究涵盖了298例住院患者的病历数据，这些患者在1972年至1982年期间接受了342次共1007次水力小肠活检。主要并发症为出血（血红蛋白浓度下降大于或等于2g/100ml），在1.5%的检查中出现。1例（0.3%）需要输血。另有1例患者（0.3%）在穿孔后需要剖腹手术。在我们的系列研究中未观察到因空肠活检导致的死亡。4例患者（1.2%）在活检后出现短暂体温大于或等于38摄氏度。其中3例患者的最终诊断为“小肠细菌过度生长”，这表明菌血症是活检后发热的原因，并且细菌过度生长易引发空肠活检的这种并发症。活检次数（n = 1 - 20）、同一患者重复检查的情况、检查年份以及营养状况与并发症的发生均无相关性。
