Linaker B D, Calam J
Gastroenterology. 1978 Oct;75(4):723-5.
Details of jejunal biopsies using the Watson small intestinal biopsy capsule done from 1966 through 1976 at three centers in Liverpool were obtained. The only complications were jejunal perforation which occurred in 2 patients over 65 years of age, 1 of whom died. This increased risk in elderly does not appear to have been previously recognized and both cases are reported. Diagnostic yield in the age group over 65 is discussed. Stricter criteria in selection of these patients for biopsy are suggested. A period of in-patient observation after biopsy in those over the age of 65 may decrease the risks of perforation. In addition, the use of a pediatric capsule, ideally with controlled suction, may lessen the risk further. The use of duodenal biopsy via an endoscope may prove to be a useful additional technique in elderly patients.
获取了1966年至1976年期间在利物浦的三个中心使用沃森小肠活检胶囊进行空肠活检的详细信息。仅有的并发症是空肠穿孔，发生在2名65岁以上的患者中，其中1例死亡。老年人的这种风险增加似乎以前未被认识到，现报告这两例病例。讨论了65岁以上年龄组的诊断率。建议在选择这些患者进行活检时采用更严格的标准。65岁以上患者活检后进行住院观察一段时间可能会降低穿孔风险。此外，使用儿科胶囊，理想情况下带有可控抽吸装置，可能会进一步降低风险。通过内窥镜进行十二指肠活检在老年患者中可能被证明是一种有用的辅助技术。
