de Rey B M, Bernaola O A, Mazzei R, Suquet G
Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Jul;50(1):111-8. doi: 10.1080/09553008614550491.
A homogeneous population of hair follicles in the rat tail has been used to analyse the in vivo response of a biological system to heavy particle irradiation. The conical configuration of the rat tail gives rise to a variable energy degradation of the beam thus yielding information on the damage elicited by the increasing l.e.t. of the helium beam at different sites on the same sample. By means of scanning electron microscopy three different zones were observed as direct evidence of helium ion penetration in the tail. Quantitative evaluation of radiation damage yielded results concerning hair follicle damage after increasing doses for different regions of the ionization curve.
大鼠尾部毛囊的均匀群体已被用于分析生物系统对重粒子辐射的体内反应。大鼠尾巴的圆锥形结构导致束流能量的可变降解，从而产生关于在同一样品的不同部位氦束线传能线密度增加所引起损伤的信息。通过扫描电子显微镜观察到三个不同区域，作为氦离子在尾部穿透的直接证据。对辐射损伤的定量评估得出了关于电离曲线不同区域剂量增加后毛囊损伤的结果。
