Clarifying the ability of NeuroD1 to convert mouse microglia into neurons.
作者信息
Matsuda Taito, Nakashima Kinichi
机构信息
Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
出版信息
Neuron. 2021 Dec 15;109(24):3912-3913. doi: 10.1016/j.neuron.2021.11.012. Epub 2021 Dec 6.
PMID:34875232
Abstract
摘要
相似文献
1
Clarifying the ability of NeuroD1 to convert mouse microglia into neurons.阐明NeuroD1将小鼠小胶质细胞转化为神经元的能力。
Neuron. 2021 Dec 15;109(24):3912-3913. doi: 10.1016/j.neuron.2021.11.012. Epub 2021 Dec 6.
2
Lineage tracing identifies in vitro microglia-to-neuron conversion by NeuroD1 expression.谱系追踪通过 NeuroD1 表达鉴定体外小胶质细胞向神经元的转化。
Genes Cells. 2023 Jul;28(7):526-534. doi: 10.1111/gtc.13033. Epub 2023 Apr 28.
3
Novel Direct Conversion of Microglia to Neurons.小胶质细胞向神经元的新型直接转化。
Trends Mol Med. 2019 Feb;25(2):72-74. doi: 10.1016/j.molmed.2018.12.005. Epub 2019 Jan 2.
4
NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming.NeuroD1可诱导小胶质细胞凋亡，且无法诱导小胶质细胞向神经元的跨谱系重编程。
Neuron. 2021 Dec 15;109(24):4094-4108.e5. doi: 10.1016/j.neuron.2021.11.008. Epub 2021 Dec 6.
5
Failure of observing NeuroD1-induced microglia-to-neuron conversion in vitro is not attributed to the low NeuroD1 expression level.体外未能观察到 NeuroD1 诱导小胶质细胞向神经元转化，这并非归因于 NeuroD1 表达水平低。
Mol Brain. 2022 Apr 5;15(1):31. doi: 10.1186/s13041-022-00912-z.
6
Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.先驱因子 NeuroD1 重排转录和表观遗传特征以执行小胶质细胞-神经元转化。
Neuron. 2019 Feb 6;101(3):472-485.e7. doi: 10.1016/j.neuron.2018.12.010. Epub 2019 Jan 9.
7
Neurod1 regulates survival and formation of connections in mouse ear and brain.Neurod1 调节小鼠耳和脑中的神经元存活和连接形成。
Cell Tissue Res. 2010 Jul;341(1):95-110. doi: 10.1007/s00441-010-0984-6. Epub 2010 May 30.
8
Generation and characterization of Neurod1-CreER(T2) mouse lines for the study of embryonic and adult neurogenesis.用于研究胚胎和成体神经发生的Neurod1-CreER(T2)小鼠品系的构建与鉴定
Genesis. 2014 Oct;52(10):870-8. doi: 10.1002/dvg.22797. Epub 2014 Jun 23.
9
Limited astrocyte-to-neuron conversion in the mouse brain using NeuroD1 overexpression.在小鼠大脑中通过过表达NeuroD1实现有限的星形胶质细胞向神经元的转化。
Mol Ther. 2022 Mar 2;30(3):982-986. doi: 10.1016/j.ymthe.2022.01.028. Epub 2022 Feb 4.
10
NeuroD1 is an upstream regulator of NSCL1.神经调节蛋白 1 是 NSCL1 的上游调节因子。
Biochem Biophys Res Commun. 2012 Mar 2;419(1):27-31. doi: 10.1016/j.bbrc.2012.01.100. Epub 2012 Jan 28.
引用本文的文献
1
Controlling the Expression Level of the Neuronal Reprogramming Factors for a Successful Reprogramming Outcome.控制神经元重编程因子的表达水平以获得成功的重编程效果。
Cells. 2024 Jul 20;13(14):1223. doi: 10.3390/cells13141223.
2
Ectopic Expression of Neurod1 Is Sufficient for Functional Recovery following a Sensory-Motor Cortical Stroke.神经分化因子1（Neurod1）的异位表达足以促进感觉运动皮层卒中后的功能恢复。
Biomedicines. 2024 Mar 15;12(3):663. doi: 10.3390/biomedicines12030663.
3
Direct neuronal conversion of microglia/macrophages reinstates neurological function after stroke.小胶质细胞/巨噬细胞的直接神经元转化可恢复中风后的神经功能。
Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2307972120. doi: 10.1073/pnas.2307972120. Epub 2023 Oct 10.
4
Expression level of the reprogramming factor NeuroD1 is critical for neuronal conversion efficiency from different cell types.重编程因子 NeuroD1 的表达水平对于不同细胞类型向神经元转化效率至关重要。
Sci Rep. 2022 Oct 26;12(1):17980. doi: 10.1038/s41598-022-22802-z.
5
Ascl1 phospho-site mutations enhance neuronal conversion of adult cortical astrocytes .Ascl1磷酸化位点突变增强成年皮质星形胶质细胞向神经元的转化
Front Neurosci. 2022 Aug 18;16:917071. doi: 10.3389/fnins.2022.917071. eCollection 2022.
6
Failure of observing NeuroD1-induced microglia-to-neuron conversion in vitro is not attributed to the low NeuroD1 expression level.体外未能观察到 NeuroD1 诱导小胶质细胞向神经元转化，这并非归因于 NeuroD1 表达水平低。
Mol Brain. 2022 Apr 5;15(1):31. doi: 10.1186/s13041-022-00912-z.
Zotero 插件