Public Laboratory, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, China.
Evidence-based Medicine Center, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai, China.
Expert Rev Vaccines. 2022 Feb;21(2):269-275. doi: 10.1080/14760584.2022.2016400. Epub 2021 Dec 19.
Concerns about the safety of the SARS-CoV-2 vaccine have been a stumbling block in the promotion of vaccination uptake. Although many studies have focused on the investigation of people's intention to receive the COVID-19 vaccine, little attention has been paid to the underlying mechanism. This study explored whether concerns about the adverse reactions to the vaccine mediated the relationship between attitudes toward the effectiveness of the vaccine and proactively taking the vaccine for family.
Questionnaires were completed by 1,673 (39.9%, 1673/4191) healthcare workers at Taizhou Hospital, Taizhou, Zhejiang, China. Among these, 1,397 (83.5%) have received two doses of the SARS-Cov-2 vaccine. Mediation analysis approach was applied in this research.
Attitudes toward the effectiveness of vaccines were positively correlated with proactively taking the COVID-19 vaccine for family. Additionally, concerns about the side effects to the SARS-Cov-2 vaccine mediated the relationship between attitudes toward the effectiveness of vaccines and proactively taking vaccines for family.
The findings imply inextricable relationships among attitudes toward the effectiveness of the SARS-Cov-2 vaccine, fears about side effects to vaccines, and taking vaccines for family. It further suggested that the importance of highlighting the safety of vaccine in promotion of vaccination uptake.
对新冠病毒疫苗安全性的担忧一直是推动疫苗接种的绊脚石。尽管许多研究都集中在调查人们对新冠疫苗的接种意愿,但对其潜在机制的关注较少。本研究旨在探讨对疫苗不良反应的担忧是否在疫苗有效性态度与主动为家人接种疫苗之间起中介作用。
本研究共调查了中国浙江台州医院的 1673 名(39.9%,1673/4191)医护人员。其中 1397 人(83.5%)已接种两剂新冠病毒疫苗。本研究采用中介分析方法。
疫苗有效性态度与主动为家人接种新冠疫苗呈正相关。此外,对新冠病毒疫苗副作用的担忧在疫苗有效性态度与主动为家人接种疫苗之间起中介作用。
这些发现表明,对新冠病毒疫苗有效性的态度、对疫苗副作用的恐惧以及为家人接种疫苗之间存在着不可分割的关系。这进一步表明,在推动疫苗接种方面,强调疫苗安全性的重要性。