因感染利什曼原虫引起皮肤利什曼病，对 2 型糖尿病患者实施的截肢手术。
Amputation of a type II diabetic patient with cutaneous leishmaniasis due to Leishmania major.
机构信息
Parasitology-Mycology Department, Avicenne Hospital, AP-HP, 125, Route de Stalingrad, Bobigny Cedex, 93009, France.
Unité des Virus Émergents (UVE: Aix-Marseille Univ-IRD 190-Inserm 1207-IHU Méditerranée Infection), Marseille, France.
出版信息
BMC Infect Dis. 2021 Dec 7;21(1):1227. doi: 10.1186/s12879-021-06909-8.
BACKGROUND
Leishmaniases are neglected tropical diseases of public health concern in Algeria. The immunocompromised patients with HIV, autoimmune diseases, or chronic alcohol abuse are at a higher risk of leishmaniasis. Herein, we present the case of an immunocompetent diabetic patient infected by Leishmania major, leading to life-threatening consequences.
CASE PRESENTATION
An Algerian diabetic patient developed a cutaneous lesion with large polymorphous inflamed granuloma and pyoderma gangrenosum in the left foot, following L. major infection. A delayed follow-up led to a treatment failure, resulting in the amputation.
CONCLUSIONS
This report highlights the absence of timely treatment of Leishmania infection as a life-threatening point among high-risk diabetic patients. Clinicians should be aware of this parasitosis leading to severe complications in diabetic patients.
背景
利什曼病是阿尔及利亚公共卫生关注的被忽视热带病。艾滋病毒、自身免疫性疾病或慢性酗酒导致免疫功能低下的患者罹患利什曼病的风险更高。在此，我们报告了一例免疫功能正常的糖尿病患者感染利什曼原虫导致危及生命的后果。
病例介绍
一名阿尔及利亚糖尿病患者在左脚感染利什曼原虫后出现皮肤病变，表现为大的多形性炎性肉芽肿和坏疽性脓皮病。由于未能及时随访，导致治疗失败并最终截肢。
结论
本报告强调了高危糖尿病患者中，未能及时治疗利什曼原虫感染是危及生命的关键点。临床医生应意识到这种寄生虫病会导致糖尿病患者出现严重并发症。
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