Guangdong Provincial Center for Disease Control and Prevention, 160 Qunxian Road, Panyu District, Guangzhou, Guangdong, China.
Department of Epidemiology and Biostatistics, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
BMC Public Health. 2021 Dec 7;21(1):2225. doi: 10.1186/s12889-021-12225-2.
The epidemiological evidence of traumatic brain injury (TBI) and spinal cord injury (SCI) mortality in mainland China is lacking. We aimed to assess the trends of TBI and SCI mortality, and their association with sex, age, location and external causes of injury in south China.
Mortality data were derived from the Disease Surveillance Points (DSPs) system of Guangdong province between 2014 and 2018. We examined the trends in mortality with Cochran-Armitage trend test, and the association between the socio-demographic factors and the TBI and SCI mortality by using negative binomial models. Subgroup analysis was performed by stratifying the external causes of TBI and SCI.
The age-standardized TBI mortality remained relatively stable (from 11.6 to 15.4 per 100,000), while the SCI mortality increased by 148.3% from 2014 to 2018. Compared with females and urban residents, the adjusted mortality rate ratios of males and rural residents were 2.3 and 2.0 for TBI, and 2.2 and 4.6 for SCI, respectively. TBI and SCI mortality increased substantially with age. Motor vehicle crashes and falls were the leading causes of TBI mortality in residents aged under 75 years and over 75 years, respectively. Falls were the most important external cause for SCI death of all ages.
Being male, rural and elderly residents are at higher risk of dying from TBI and SCI. The substantial burden of TBI and SCI caused by road traffic crashes and falls has called for the urgent need to improve injury prevention, pre-hospital aid, hospital treatment and recovery.
中国大陆创伤性脑损伤（TBI）和脊髓损伤（SCI）死亡率的流行病学证据不足。我们旨在评估华南地区 TBI 和 SCI 死亡率的趋势及其与性别、年龄、地点和损伤外部原因的关系。
死亡率数据来自广东省疾病监测点（DSPs）系统，时间范围为 2014 年至 2018 年。我们使用 Cochran-Armitage 趋势检验检查死亡率趋势，并使用负二项模型检查社会人口因素与 TBI 和 SCI 死亡率之间的关系。通过分层 TBI 和 SCI 的外部原因进行亚组分析。
年龄标准化的 TBI 死亡率相对稳定（从 11.6 至 15.4/10 万），而 SCI 死亡率从 2014 年到 2018 年增加了 148.3%。与女性和城镇居民相比，男性和农村居民的 TBI 死亡率调整后的比率分别为 2.3 和 2.0，SCI 死亡率分别为 2.2 和 4.6。TBI 和 SCI 死亡率随年龄增长而显著增加。机动车事故和跌倒分别是 75 岁以下和 75 岁以上居民 TBI 死亡的主要原因。跌倒是所有年龄段 SCI 死亡的最重要外部原因。
男性、农村和老年居民死于 TBI 和 SCI 的风险更高。道路交通事故和跌倒造成的 TBI 和 SCI 负担沉重，迫切需要加强伤害预防、院前急救、医院治疗和康复。
