Carbone Roberto G, Villa Giuseppe, Negrini Simone, Puppo Francesco
Departments of Internal Medicine, University of Genoa, Genoa, Italy.
Nuclear Medicine, University of Genoa, Genoa, Italy.
Radiol Case Rep. 2021 Nov 27;17(2):340-343. doi: 10.1016/j.radcr.2021.10.040. eCollection 2022 Feb.
Sarcoidosis is a granulomatous disease of unknown etiology. At present the best diagnostic imaging procedure to assess stage and activity of sarcoidosis is controversial. We report the case of a 50-year-old male admitted with a history of dyspnea and fatigue with past medical history negative for smoking, occupational and environmental risk factors. Physical examination, routine blood tests, and pulmonary function tests were normal except for hypercalciuria. A chest radiograph showed bilateral hilar lymphadenopathy. Single photon emission computed tomography and/or computed tomography (SPECT and/or CT) In-111 Octreotide (Octreoscan) scintigraphy confirmed morphologic involvement of bilateral hilar lymph nodes and a mediastinoscopy biopsy specimen provided diagnosis of pulmonary sarcoidosis (stage 0). This clinical case shows the effectiveness of In-111 Octreotide SPECT and/or CT in the early diagnosis of pulmonary sarcoidosis.
结节病是一种病因不明的肉芽肿性疾病。目前,用于评估结节病分期和活动度的最佳诊断成像方法存在争议。我们报告了一例50岁男性病例,该患者因呼吸困难和疲劳入院,既往病史显示无吸烟、职业和环境风险因素。体格检查、常规血液检查和肺功能测试均正常,仅尿钙增多。胸部X线片显示双侧肺门淋巴结肿大。单光子发射计算机断层扫描和/或计算机断层扫描(SPECT和/或CT)In-111奥曲肽(Octreoscan)闪烁显像证实双侧肺门淋巴结有形态学改变,纵隔镜活检标本确诊为肺结节病(0期)。该临床病例显示了In-111奥曲肽SPECT和/或CT在肺结节病早期诊断中的有效性。