Zamora Diana I, Gonzalez Laura M
General Medicine, Universidad de Ciencias Medicas, San Jose, CRI.
Cureus. 2021 Dec 5;13(12):e20176. doi: 10.7759/cureus.20176. eCollection 2021 Dec.
Thrombotic thrombocytopenic purpura (TTP) is a type of thrombotic microangiopathy (TMA) related to a deficiency of ADAMTS13 protein, which could lead to fatal outcomes. TTP presents a vast array of symptoms, making its diagnosis a challenge to physicians. In this report, we discuss the case of an 80-year-old male who presented with abdominal pain and hypertension with underlying severe thrombocytopenia and hemolysis. Although his presentation could also be secondary to malignant hypertension, he was promptly diagnosed with TTP based on these findings. TTP is a hematologic emergency, and it should be kept in the differential diagnosis when a patient presents with thrombocytopenia and hemolysis with or without accompanying symptoms.
血栓性血小板减少性紫癜（TTP）是一种与ADAMTS13蛋白缺乏相关的血栓性微血管病（TMA），可导致致命后果。TTP症状繁多，给医生的诊断带来挑战。在本报告中，我们讨论了一名80岁男性患者的病例，该患者出现腹痛和高血压，伴有严重血小板减少和溶血。尽管他的症状也可能继发于恶性高血压，但基于这些发现，他被迅速诊断为TTP。TTP是一种血液学急症，当患者出现血小板减少和溶血，伴或不伴有其他症状时，应将其纳入鉴别诊断。
