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不同漂白剂电位和pH值的时间变化评估。

Assessment of the temporal variation of electrical potential and pH of different bleaching agents.

作者信息

Pretel Hermes, Lucas de Sousa Gomes Costa Joatan, Esteban Florez Fernando Luis, Nogueira Básia Rabelo, Batista de Oliveira Junior Osmir

机构信息

São Paulo State University - UNESP, Department of Restorative Dentistry, School of Dentistry, Araraquara, São Paulo, 14801-903, Brazil.

The University of Oklahoma Health Sciences Center, Department of Restorative Sciences, Division of Dental Biomaterials, College of Dentistry, 1201 N. Stonewall Avenue, Oklahoma City, Oklahoma, 73117, USA.

出版信息

Heliyon. 2021 Nov 23;7(11):e08452. doi: 10.1016/j.heliyon.2021.e08452. eCollection 2021 Nov.

Abstract

INTRODUCTION

Tooth whitening procedures are under continuous investigation to improve esthetic outcomes and reduce bleaching sensitivity (BS) precipitating from treatments. During the dental bleaching process it is known that the release of free radicals degrades the organic pigment molecules of the tooth and with this an amount of energy is released. Nonetheless, previous studies have never investigated the temporal correlation between of pH and electric potential (EP) generated in this treatment.

OBJECTIVES

Therefore, the objective of the present study was to investigate temporal variations of pH and EP associated with three different commercially available bleaching gels and the correlation levels between parameters of interest to provide relevant information regarding the kinetics of oxidation reactions in dental bleaching procedures.

METHODS

The study was divided into 3 groups (n = 9) in function of hydrogen peroxide concentration (either 6%, 15% and 35%). The temporal evolution of pH and EP values were determined using a highly-accurate and previously calibrated pH meter at specific time-points (5, 10, 15 and 30 min).

RESULTS

Data obtained were submitted to one-way ANOVA of repeated measures with Bonferroni post-test (α = 0.05). The results of the study showed difference in the factor gel concentration (p < 0,0001), time (p < 0,0001) and interaction (gel/time) (p = 0.002) while throughout the intervals evaluated the groups remained relatively stable and without significant difference in the intragroup variation of pH (p < 0.05) and in EDP only with significant difference in the 5 min interval of the 35% concentration. A 2nd order polynomial relationship test showed high correlation levels.

CONCLUSION

It can thus be concluded that there is a negative relationship between EP and pH variation in the different gel concentrations.

CLINICAL SIGNIFICANCE

The findings of the present study suggest that bleaching gels of higher concentration may provoke BS that are more intense and durable due to significant electric depolarization of neuronal extensions of pulpal tissues.

摘要

引言

牙齿美白程序一直在不断研究中,以改善美学效果并降低治疗引起的漂白敏感性(BS)。在牙齿漂白过程中,已知自由基的释放会降解牙齿的有机色素分子,并释放出一定量的能量。然而,以往的研究从未调查过该治疗过程中产生的pH值与电势(EP)之间的时间相关性。

目的

因此,本研究的目的是调查与三种不同市售漂白凝胶相关的pH值和EP的时间变化,以及相关参数之间的相关水平,以提供有关牙齿漂白程序中氧化反应动力学的相关信息。

方法

根据过氧化氢浓度(6%、15%和35%)将研究分为3组(n = 9)。使用高精度且预先校准的pH计在特定时间点(5、10、15和30分钟)测定pH值和EP值的时间演变。

结果

所获得的数据进行了重复测量的单因素方差分析,并进行了Bonferroni事后检验(α = 0.05)。研究结果显示,凝胶浓度因素(p < 0,0001)、时间(p < 0,0001)和相互作用(凝胶/时间)(p = 0.002)存在差异,而在整个评估区间内,各组相对稳定,组内pH值变化(p < 0.05)和EDP仅在35%浓度的5分钟区间存在显著差异。二阶多项式关系检验显示出高度相关水平。

结论

因此可以得出结论,不同凝胶浓度下EP与pH值变化之间存在负相关关系。

临床意义

本研究结果表明,由于牙髓组织神经元延伸的显著电去极化,较高浓度的漂白凝胶可能引发更强烈且持久的BS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ac1/8628040/8e30e6eb2c8f/gr1.jpg

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