Clinical Laboratories, Charles River Laboratories - ULC, Senneville, Quebec, Canada.
Labcorp Drug Development, Madison, Wisconsin, United States.
ILAR J. 2021 Dec 31;62(1-2):203-222. doi: 10.1093/ilar/ilab028.
Clinical pathology testing for investigative or biomedical research and for preclinical toxicity and safety assessment in laboratory animals is a distinct specialty requiring an understanding of species specific and other influential variables on results and interpretation. This review of clinical pathology principles and testing recommendations in laboratory animal species aims to provide a useful resource for researchers, veterinary specialists, toxicologists, and clinical or anatomic pathologists.
临床病理学检测在用于研究或生物医学研究,以及用于实验室动物的临床前毒性和安全性评估方面是一个独特的专业领域,需要了解对结果和解释有影响的物种特异性和其他变量。本文回顾了实验室动物物种的临床病理学原则和检测建议,旨在为研究人员、兽医专家、毒理学家以及临床或解剖病理学家提供有用的资源。