Department of Fine Chem., Seoul National Univ. of Sci. and Tech. (SNUT), Seoul, South Korea.
Luminescence. 2022 Feb;37(2):332-339. doi: 10.1002/bio.4175. Epub 2021 Dec 29.
SBOD (sodium (E)-2-(3-[5-bromothiophen-2-yl]-3-oxoprop-1-en-1-yl)-4,6-dichlorophenolate) was designed and synthesized as a chalcone-based fluorescent turn-on chemosensor for Mg and Cd . SBOD selectively detected Mg and Cd through the increase in effective fluorescence. Detection limits of SBOD for Mg and Cd were calculated to be 3.8 μM and 2.9 μM, respectively. The binding modes of SBOD for Mg and Cd were determined to be 1:1 by ESI-MS and Job plot. Association mechanisms for SBOD to Mg and Cd were illustrated by ESI-MS, UV-vis, fluorescence spectroscopy, and calculations.
SBOD（钠（E）-2-（3-[5-溴噻吩-2-基]-3-氧代丙-1-烯-1-基）-4,6-二氯苯氧酸盐）被设计并合成，作为一种基于查尔酮的荧光开启型化学传感器，用于 Mg 和 Cd。SBOD 通过有效荧光的增加来选择性地检测 Mg 和 Cd。计算出 SBOD 对 Mg 和 Cd 的检测限分别为 3.8 μM 和 2.9 μM。通过 ESI-MS 和 Job 图确定了 SBOD 与 Mg 和 Cd 的结合模式为 1:1。通过 ESI-MS、UV-vis、荧光光谱和计算，说明了 SBOD 与 Mg 和 Cd 的结合机制。
