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巴西供体肝脏的处理:如何优化移植中的利用率?

Disposal of donor livers in Brazil: how to optimize their utilization rate in transplants?

机构信息

Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

出版信息

Einstein (Sao Paulo). 2021 Dec 3;19:eAO6770. doi: 10.31744/einstein_journal/2021AO6770. eCollection 2021.

Abstract

OBJECTIVE

To understand the professionals´ perception of the use of deceased donor liver for transplantation, the reasons to decline them, and propose strategies to increase their use safely.

METHODS

This is a cross-sectional, descriptive qualitative-quantitative study. Professionals working with liver transplantation answered a self-administered, structured, and electronic questionnaire comprising 17 questions distributed into four sessions (demographic factors, perception of use of organs, reasons for disposal, and measures to favor their usage).

RESULTS

A total of 42 professionals participated in the study. The rate of use of organs was considered low by 71.43% (n=30) of respondents or very low by 19.05% (n=8). Everyone agreed that it was possible to increase it. Thirty-one (73.81%) participants believed the expansion of the population of extended criteria donors affected this index negatively. Donor-related conditions were the most frequent category of reasons for refusing a liver for transplantation, being the findings during organ retrieval the most frequent reason in clinical practice. Enhanced training of intensive care teams in the treatment of donors was the primary measure selected to favor the use of the organs, followed by investment in new technologies to optimize its preservation/evaluate its function before transplantation.

CONCLUSION

Implementation of strategies to increase the rate of acceptance of livers is expected. Improvements in donor intensive care and implementation of new preservation technologies should favor the use of the organs.

摘要

目的

了解专业人士对使用已故供体肝脏进行移植的看法、拒绝使用的原因,并提出安全增加其使用量的策略。

方法

这是一项横断面、描述性定性-定量研究。参与肝脏移植的专业人员回答了一份自我管理、结构化和电子问卷,共包含 17 个问题,分为四个部分(人口统计学因素、对器官使用的看法、处置原因和有利于其使用的措施)。

结果

共有 42 名专业人员参与了研究。71.43%(n=30)的受访者认为器官使用率较低,19.05%(n=8)的受访者认为非常低。每个人都认为可以提高这个比例。31 名(73.81%)参与者认为扩展标准供体人群的增加对这个指标产生了负面影响。供体相关条件是拒绝移植肝脏的最常见原因类别,在临床实践中,器官采集期间的发现是最常见的原因。增强重症监护团队在供者治疗方面的培训是优先选择的增加器官使用的措施,其次是投资新技术以优化其保存/在移植前评估其功能。

结论

预计将实施增加肝脏接受率的策略。提高供者重症监护水平和实施新的保存技术应有利于器官的使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be26/8670423/315720864820/2317-6385-eins-19-eAO6770-gf01.jpg

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