The Edinburgh Shoulder Clinic, New Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
J Bone Joint Surg Am. 2022 Jan 19;104(2):123-138. doi: 10.2106/JBJS.20.02018.
The functional outcome following nonoperative treatment of a proximal humeral fracture and the factors that influence it are poorly defined. We aimed to prospectively assess patient-reported outcome measures (PROMs) in a patient cohort at 1 year after the injury.
In this study, 774 adult patients sustaining a proximal humeral fracture completed PROM assessments, including the Oxford Shoulder Score (OSS), the EuroQol-5 Dimensions-3 Levels (EQ-5D-3L), and visual analog scale (VAS) assessments of pain, health, and overall treatment satisfaction at 1 year. The mean patient age was 65.6 years, and 73.8% of patients were female. The influences of demographic and fracture measurements and complications on the OSS and EQ-5D-3L were assessed.
The 1-year mean scores were 33.2 points (95% confidence interval [CI], 32.1 to 34.2 points) for the OSS and 0.58 (95% CI, 0.55 to 0.61) for the EQ-5D-3L. There was considerable heterogeneity in the reported scores, and the 3 demographic variables of higher levels of dependency, higher levels of social deprivation, and a history of affective (mood) disorder were most consistently associated with poorer outcomes, accounting for between 37% and 43% of the score variation. The initial fracture translation potentially leading to nonunion accounted for 9% to 15% of the variation, and a displaced tuberosity fracture was also predictive of 1% to 4% of the outcome variation. There was evidence of a ceiling effect for the OSS, with 238 patients (30.8%) having a score of ≥47 points but a mean outcome satisfaction of only 72.9 points, and this effect was more pronounced in younger, active individuals. At the other end of the spectrum, 239 patients (30.9%) reported an OSS of ≤24 points, and 120 patients (15.5%) had a "worse-than-death" EQ-5D-3L score.
Nonoperative treatment of proximal humeral fractures produces considerable variation in shoulder-specific and general health outcomes at 1 year, and a substantial proportion of patients have poor perceived functional outcomes. The outcome for the majority of less-displaced fractures is mainly influenced by preexisting patient-related psychosocial factors, although the fracture-related factors of displacement, nonunion, and tuberosity displacement account for a small but measurable proportion of the variation and the poorer outcomes in the minority with more severe injuries.
Prognostic Level I. See Instructions for Authors for a complete description of levels of evidence.
非手术治疗肱骨近端骨折的功能预后及其影响因素尚未明确。本研究旨在前瞻性评估患者损伤后 1 年的患者报告结局测量(PROM)。
本研究纳入 774 例肱骨近端骨折成年患者,在损伤后 1 年完成 PROM 评估,包括牛津肩肘评分(OSS)、欧洲五维健康量表 3 级(EQ-5D-3L)和疼痛、健康和总体治疗满意度的视觉模拟评分(VAS)。患者平均年龄为 65.6 岁,73.8%为女性。评估了人口统计学和骨折测量及并发症对 OSS 和 EQ-5D-3L 的影响。
OSS 的 1 年平均评分为 33.2 分(95%置信区间,32.1 至 34.2 分),EQ-5D-3L 为 0.58(95%置信区间,0.55 至 0.61)。报告的评分存在较大异质性,3 个人口统计学变量,即依赖性更高、社会剥夺程度更高和情感(情绪)障碍病史,与较差的结局最一致,占评分变化的 37%至 43%。初始骨折移位可能导致骨折不愈合,占 9%至 15%的变化,肩袖突骨折也是 1%至 4%的结局变化的预测因素。OSS 存在天花板效应的证据,238 例患者(30.8%)OSS 评分≥47 分,但总体治疗满意度仅为 72.9 分,这种效应在年轻、活跃的个体中更为明显。在谱的另一端,239 例患者(30.9%)OSS 评分≤24 分,120 例患者(15.5%)EQ-5D-3L 评分“比死亡还差”。
肱骨近端骨折的非手术治疗在 1 年时会导致肩部特异性和总体健康结局出现较大差异,且相当一部分患者的功能预后较差。大多数移位较轻的骨折的结局主要受患者先前存在的社会心理因素影响,尽管骨折相关因素,如移位、骨折不愈合和肩袖突移位,占变化的一小部分,但在少数严重损伤的患者中,这些因素与较差的结局相关。
预后水平 I。请参阅作者说明以获取完整的证据水平描述。