Sze G, De Armond S J, Brant-Zawadzki M, Davis R L, Norman D, Newton T H
AJR Am J Roentgenol. 1986 Aug;147(2):331-7. doi: 10.2214/ajr.147.2.331.
Review of all normal magnetic resonance (MR) scans performed over a 12-month period consistently revealed punctate areas of high signal intensity on T2-weighted images in the white matter just anterior and lateral to both frontal horns. Normal anatomic specimens were examined with attention to specific characteristics of this region. Three unique features typify the brain tissues that correspond to the foci of high signal. First, this region of the brain is notable for its loose network of axons with low myelin content. Second, pathologic scrutiny revealed an entity called "ependymitis granularis," which represents patchy loss of the ependyma in the frontal horns with astrocytic gliosis. Third, flow of interstitial fluid within this region of the brain tends to converge at the dorsal-lateral angle of the frontal horns. All these factors contribute to increased water content locally, which results in foci of high signal intensity anterior to the frontal horns in all normal MR scans.
对在12个月期间进行的所有正常磁共振（MR）扫描的回顾一致显示，在双侧额叶角前方和外侧的白质中，T2加权图像上有散在的高信号强度区域。对正常解剖标本进行了检查，并关注该区域的特定特征。对应于高信号灶的脑组织具有三个独特特征。首先，该脑区以其轴突网络疏松、髓磷脂含量低而著称。其次，病理检查发现一种名为“颗粒性室管膜炎”的病变，表现为额叶角室管膜的片状缺失伴星形细胞胶质增生。第三，该脑区的间质液流动倾向于在额叶角的背外侧角汇聚。所有这些因素都导致局部含水量增加，这在所有正常MR扫描中都导致额叶角前方出现高信号强度灶。
