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使用机器学习预测青少年的短期自杀意念:开发决策工具以识别住院后每日风险水平。

Predicting short-term suicidal thoughts in adolescents using machine learning: developing decision tools to identify daily level risk after hospitalization.

机构信息

Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.

Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.

出版信息

Psychol Med. 2023 May;53(7):2982-2991. doi: 10.1017/S0033291721005006. Epub 2021 Dec 9.

Abstract

BACKGROUND

Mobile technology offers unique opportunities for monitoring short-term suicide risk in daily life. In this study of suicidal adolescent inpatients, theoretically informed risk factors were assessed daily following discharge to predict near-term suicidal ideation and inform decision algorithms for identifying elevations in daily level risk, with implications for real-time suicide-focused interventions.

METHODS

Adolescents ( = 78; 67.9% female) completed brief surveys texted daily for 4 weeks after discharge ( = 1621 observations). Using multi-level classification and regression trees (CARTSs) with repeated 5-fold cross-validation, we tested (a) a simple prediction model incorporating previous-day scores for each of 10 risk factors, and (b) a more complex model incorporating, for each of these factors, a time-varying person-specific mean over prior days together with deviation from that mean. Models also incorporated missingness and contextual (study week, day of the week) indicators. The outcome was the presence/absence of next-day suicidal ideation.

RESULTS

The best-performing model (cross-validated AUC = 0.86) was a complex model that included ideation duration, hopelessness, burdensomeness, and self-efficacy to refrain from suicidal action. An equivalent model that excluded ideation duration had acceptable overall performance (cross-validated AUC = 0.78). Models incorporating only previous-day scores, with and without ideation duration (cross-validated AUC of 0.82 and 0.75, respectively), showed relatively weaker performance.

CONCLUSIONS

Results suggest that specific combinations of dynamic risk factors assessed in adolescents' daily life have promising utility in predicting next-day suicidal thoughts. Findings represent an important step in the development of decision tools identifying short-term risk as well as guiding timely interventions sensitive to proximal elevations in suicide risk in daily life.

摘要

背景

移动技术为监测日常生活中的短期自杀风险提供了独特的机会。在这项对自杀青少年住院患者的研究中,我们在出院后每天评估基于理论的风险因素,以预测近期自杀意念,并为识别日常风险水平升高提供决策算法,这对实时关注自杀的干预措施具有重要意义。

方法

青少年(n=78;67.9%为女性)在出院后 4 周内每天完成简短的调查(共 1621 次观察)。我们使用具有重复 5 折交叉验证的多级分类和回归树(CARTS),检验了(a)一种简单的预测模型,该模型纳入了 10 个风险因素中每个因素的前一天得分,以及(b)一种更复杂的模型,该模型纳入了对于每个因素,前几天的个体特定均值及其与该均值的偏差。模型还纳入了缺失值和情境(研究周、星期几)指标。因变量是次日是否存在自杀意念。

结果

表现最佳的模型(交叉验证 AUC=0.86)是一种复杂模型,其中包括意念持续时间、无望感、负担感和抑制自杀行为的自我效能感。排除意念持续时间的等效模型表现出可接受的整体性能(交叉验证 AUC=0.78)。仅纳入前一天得分的模型,以及包含和不包含意念持续时间的模型(交叉验证 AUC 分别为 0.82 和 0.75),其表现相对较弱。

结论

结果表明,在青少年日常生活中评估的特定动态风险因素组合在预测次日自杀念头方面具有很大的应用潜力。这些发现代表了开发识别短期风险的决策工具以及指导对日常生活中自杀风险升高的及时干预的重要一步,这些干预措施对近测风险升高敏感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7ec/10235658/e944918aa805/S0033291721005006_fig1.jpg

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